Urinary Bladder Infection:
E. Coli Uropathogenic Bacteria

E. Coli: The Most Common Cause of UTI

In most cases, about 80 percent, urinary tract infection in adults is caused by a variety of pathogens - infectious bacteria - normally present in the intestines, especially in the rectum (colon).

Nearly all infections of the lower urinary tract and bladder are caused by a few strains of E. coli bacteria - uropathogenic Escherichia coli (UPEC).

Various harmless strains of E. coli are normally present in the body - but they do not belong in the urinary tract.

Theses bacteria have multiple little hairs called cilia that function like little feet that allow them to climb from the skin around the vagina, up the urinary tube, into the bladder.

If E. coli get into the bladder or the urethra (tube that carries urine from the bladder), the body has ways of fighting them off - including the obvious methods of simply flushing them out with the urine.

These bacteria, however, have evolved ways of anchoring themselves to the cells of the urinary tract.

The invading E. coli take advantage of receptors naturally found on the cells of the mucosal lining of the urinary tract. (Receptors are like molecular "docking bays" for substances which the cells need for their normal growth and development).

Like pirates in an old movie, E. coli use "grappling hooks", called type I pili, to first hook on to these receptors, and then to invade the cell. (These pathogenic "grappling hooks" are composed of long, fibrous chains of a molecular "glue" called adhesin).

Once inside the cell, E. coli can live and reproduce in safety, shielded from many of the body's defensive immune responses.

In fact, they are so sophisticated that when the body detects that cells have been infected and activates the cell suicide program to destroy the bacteria, E. coli can actually flee the dying host cell before it is flushed out - and look for new cells to invade!

Repeated Bladder Infections

For many women - especially those over the age of 55 years or between the ages of 25 and 29 - repeated bladder infections can be a painful and frustrating battle.

Women who have had three or more (3+) infections a year are likely to continue having them. In other words, they can get another infection within 18 months of the last one, or even more requently.

Possible multiple factors behind recurrent urinary tract infections include:

• the ability of E. coli bacteria to attach to cells lining the urinary tract
• chemical irritation due to commercial toiletries, such as bath additives and washing powders
• the separate infections, stemming from a strain or type of bacteria different from the infection before (even when several urinary tract infections in a row are due to E. coli, slight differences in the bacteria indicate distinct infections), and
• the inadequacy of the current standard drug (antibiotic) treatments for urinary bladder infections.

Some women, however, have recurrent symptoms suggestive of urinary tract infection - but without infection being present. Although this condition is not serious, it can be troublesome.

Because of the chance of kidney infection (pyelonephritis), repeated or chronic urinary tract infections should be treated thoroughly.

Survival Rate of E. Coli Bacteria

They are able to survive antibiotic treatment for bladder infections by reverting to an inactive state. Within several days of antibiotic treatment, the number of bacteria reproducing drop to zero.

Not all the E. coli bacteria are killed, though.

After an antibiotic treatment, uropathogenic E. coli may be still present in a dormant state and linger in the urinary tract:

• about 3 percent after ciprofloxacin hydrochloride (Cipro) treatment and
• about 7 percent after trimethoprim-sulfamethoxazole, a popular two-drug (Bactrim/Septra) treatment.

Even after a month of antibiotic exposure, about 10 million of the original 1 billion bacteria may remain in the urinary tract.

Antibiotic treatment does NOT successfully kill all the bacteria participating in the infection and may, in fact, encourage many of the bacteria to persist in a resting state.

Therefore, current standard drug treatments for bladder infections are not adequate and this phenomenon may account for many of the repeat urinary tract infections.

New Antibiotic-Resistant Strain of E. Coli

The analyzed strain, resistant to trimethoprim-sulfamethoxazole, a popular two-drug antibacterial combination (Bactrim/Septra), shows a pattern of resistance to multiple antibiotics and has genetic characteristics called "virulence factors" that increase its ability to infect the urinary tract.

Not much is known about how new strains of bacteria that infect the urinary tract arise and spread. There is also no evidence that the new strain of E. coli is causing any increase in kidney infections or other serious complications.

It could be that this organism has been around forever and has now acquired resistance to several antibiotics. It could have been introduced, perhaps through contaminated food.

D-Mannose: The Natural Alternative to Antibiotics

Even more remarkably, D-mannose accomplishes this feat without killing a single bacterium! (Exactly how does this it will be explained later).

Suffice it to say that, because it gets rid of bladder infection-causing bacteria without committing "bactericide," people who use it suffer none of the unwanted side effects of antibiotics:

• no gastrointestinal (GI) problems,
• no yeast infections, and
• no resistant bacteria.

In fact, D-mannose has no adverse side effects of any kind.

It Tastes Good!
As a bonus, D-mannose actually tastes good. Where a "spoonful of sugar" helped the medicine go down in Mary Poppin's day, with D-mannose, a spoonful of sugar IS the medicine.

It Is Effective and Safe!
Because it is so effective and so benign, women (even pregnant women) who are susceptible to recurrent bladder infections, can safely take D-mannose as a preventive measure to head off future attacks.

It Is Suitable for Children
D-mannose is also ideally suited for children with bladder infections. Because it tastes so good (it is a sugar, after all!), children actually enjoy taking it.

It Is Just As Effective As Antibiotics
Although D-mannose is virtually unknown to practitioners of conventional medicine, many research reports have demonstrated its mode of action and effectiveness against E. coli, the microorganism that causes most bladder infections.

Moreover, nearly 15 years of clinical experience have shown that it is just about as effective at curing bladder infections as antibiotic drugs.

It Has No Known Drawbacks
At first glance, D-mannose may sound too good to be true: a "medicine" that's highly effective, perfectly safe, pleasant to use, inexpensive, and available without a doctor's prescription. Yet, it is true!

Unlike virtually any conventional medication, and many natural or "alternative" treatments as well, D-mannose has no known drawbacks.

E. Coli Bacterial Infections

The urinary tract reacts to a bacterial infection in much the same way that the upper respiratory system reacts to a cold virus. The tissues become inflamed, irritated, and swollen. Just as it's hard to breathe through swollen and inflamed nasal passages, swollen and inflamed urinary ducts can partially obstruct normal flow, making it painful and difficult to pass urine.

Built-In Safeguards
Ordinarily, the urinary system is hostile territory for bacteria, viruses, or any other microorganisms.

Bugs that do make their way into a healthy urinary tract are likely to find an inhospitable acidic environment (pH <5.5).

Bugs are also subject to attack by the body's immune defenses. (Adult men have the added protection of a specific bacterial growth inhibitor squirted directly into the urinary system by their prostate gland.)

Even if microorganisms manage to overcome these considerable obstacles, they would typically be flushed out with the normal flow of urine. So effective are these natural antibacterial defenses that in a study in which bacteria were instilled directly into the bladders of guinea pigs, simple urination expelled 99.9 percent of the bugs.

Despite all these built-in safeguards; each year millions of people, overwhelmingly women, still develop bladder infections.

Urethritis
Most bladder infections begin when bacteria originating in the bowels travel to and grow in the urethra. Infections limited to the urethra are known as "urethritis."

Cystitis
When bacteria travel upstream to the bladder, the infection is called "cystitis."

Nephritis
Infections that reach the kidneys are known as "nephritis" or "pyelonephritis."

The E. coli that cause most bladder infections are among the most common friendly bacteria in the gastrointestinal (GI) tract, where they aid digestion, produce a few vitamins, and in general, behave themselves without bothering us.

However, when E. coli and other bugs exit the lower GI tract, they may gain entry to the urinary tract via the urethra, where they may attach to the internal lining of the bladder, multiply, and spread.

Other Infectious Bacteria
Although up to 90 percent of bladder infections are caused by E. coli, the remaining 10 percent are caused by bacteria known as

• Chlamydia
• Mycoplasma
• Neisseria gonorrhea
• and others.

Unlike E. coli, these bugs tend to be transmitted via sexual contact and rarely cause the more serious bladder and kidney infections.

Still, all of these non-E. coli infections combined amount to no more than 10 percent of all bladder infections.

Bladder Infection Treatment With D-Mannose

While there's nothing essentially wrong with killing disease-causing bacteria, this approach does have some very serious drawbacks, as we have noted earlier. Happily, "bacteria-cide" is not the only possible avenue of attack.

More Natural Way
Another, more natural way to eliminate E. coli infections from the urinary tract is to beat them at their own game. If they're going to cause trouble, bacteria usually have to find a way to adhere (stick) to the body tissue they're infecting. In bladder infection, E. coli attach to cells lining the bladder and urinary tract using filmy, hair-like projections called fimbria on their cell walls.

At the tip of each fimbrium is a glycoprotein (a combination carbohydrate and protein) called a lectin that is programmed to bind to the first molecule of the sugar mannose that it encounters.

It turns out that molecules of mannose (produced inside urinary tract lining cells) naturally dot the surfaces of these cells. Here they act as "receptors," inviting the fimbria of E. coli to attach, and allowing them to bind to the tissue in a tight, Velcro-like grip.

If not for this attachment to the cell's mannose, any E. coli that had successfully ventured up the urethral river would be unable to stick to the slippery surface and would be washed right back out on the next tide of urination.

How Does D-Mannose Work?

The E. coli couldn't turn around without bumping into D-mannose "just floating around" in the urine. Unable to resist the tasty bait they suddenly find themselves swimming in, they would latch onto the nearest mannose molecules, and happily sail off into the porcelain sunset.

Those few E. coli left clinging to mannose molecules on cells then become easy prey for white blood cells and other agents of the immune system.

E. Coli Coated With D-Mannose
In addition to its natural occurrence in the cells lining the epithelial tract, the sugar D-mannose is also found in relatively large quantities in fruit such as peaches, apples, oranges, and certain berries, like cranberries and blueberries.

Extracted in the form of D-mannose, a white crystal sugar similar to glucose, it can be easily dissolved in a liquid and swallowed. (Mannose can also be synthesized from other simple sugars.)

When someone with bladder infection consumes a dose of D-mannose, the sugar is absorbed in the upper GI tract, but at a much slower rate than most other sugars. (For example, glucose is absorbed more than eight times faster.)

Moreover, unlike other sugars, D-mannose is not readily converted to glycogen (and stored) in the liver, but instead passes directly into the bloodstream largely unchanged.

As the D-mannose-laden blood passes through the kidneys, a considerable proportion of the sugar is extracted and added to the urine.

The D-mannose-sweetened urine flows from the kidneys through the ureters to the bladder and on to the urethra, literally sugar-coating any free-floating E. coli it might encounter, so they can't stick to cells any more.

It also unsticks most of the E. coli already "Velcro-ed" to the inner surface of the bladder and urinary tract, ultimately flushing them all down the drain.

It Is Scientifically Proven
First, the "molecular mechanism" of the action of D-mannose on E. coli is scientifically proven. There's no argument at all about this among researchers who have studied it.

Second, literally tens of thousands of women working with natural medicine doctors have successfully applied this science to their own bladder infections.

Therapeutic Value of D-Mannose
Considerable circumstantial evidence, combined with common sense and over 15 years of clinical experience, makes a compelling case for the therapeutic value of D-mannose.

Laboratory Studies
In one laboratory study, for example, rats' urinary tracts were inoculated with E. coli. Within one day, those rats also given D-mannose were found to have significantly lower levels of bacteria in their urine.

In another study, administering a mannose-like substance (niethyl a-D-mannopyranoside) to E. coli-infected mice led to a 90 percent reduction in bacterial attachment to the urinary tract.

Research in humans shows that ingesting D-mannose significantly elevates blood mannose levels, a prerequisite if urinary levels are to rise.

Epidemiological Evidence
Perhaps the best available evidence, though, comes from the experience of people who have used it. Natural medicine-oriented physicians have been recommending D-mannose to people with bladder infection since the mid-1980s with great success.

A 5-Year-Old Girl
For example, in one case, a 5-year-old girl had almost continuous bladder infections for her entire life that had failed to respond to every antibiotic therapy her physicians tried (72 doctors in all!).

At the end of their rope, her doctors were now considering a kidney transplant, since her kidneys were starting to fail due to years of chronic infection.

Since urine culture showed her bladder infection was due to E. coli, she was started on D-mannose (1 tsp in a glass of water every 2-3 hours). Within 48 hours, her infection had vanished, and her kidneys were saved!

"Honeymoon Cystitis"
D-mannose can also be very effective in cases of "honeymoon cystitis." It's not uncommon for women to avoid sex because they get a bladder infection nearly "every time" they have intercourse.

If a urine culture shows the presence of E. coli, taking D-mannose, 1 teaspoon 1 hour prior to intercourse, will mostly likely completely eliminate further infections.

Recurrent Bladder Infections
Physicians experienced with D-mannose report that women prone to very frequent recurrent bladder infections that are not necessarily related to sexual intercourse can also often benefit from taking D-mannose preventively. To save expense, some women have been able to "taper down" their dosage and dose frequency.

Single Bladder Infections
By far the most frequent success with D-mannose has been achieved by the thousands of women who have suffered single (non-recurrent) episodes of bladder infection.

In over 90 percent of such cases, 1 teaspoon of D-mannose every 2 to 3 hours usually clears the infection in 1 to 3 days.

Try D-Mannose PLUS First

Ninety percent of the time, bladder infection is caused by E. coli and will respond to D-mannose Plus treatment with significant symptom reduction within 24 hours.

PLEASE NOTE: Even though symptoms are improved within 24 hours, D-mannose Plus should be continued for 2 to 3 days after the last symptom is gone, just to "make sure."

A Word of Caution
If a bladder infection treated with D-mannose Plus does not show significant improvement within 24 hours (about 10 percent of cases), it is likely that the causative organism is not E. coli, and consider using herbal remedies, such as Uribiotic Formula, B.L.D.R. Liquid Remedy and/or Pure Essential Oil of Wild Oregano, as the infection can spread into the upper urinary tract, namely, the kidneys, causing serious problems.

D-Mannose Powder PLUS: Dietary Supplement

Serving Size: 1 Level Teaspoon (4.7 grams)
Servings Per Container: 30

Amount Per Serving:

• D-Mannose: 1,500 mg
• Cranberry Extract (Vaccinium macrocarpon) (Fruit): 800 mg
• Vitamin C (as ascorbic acid): 60 mg

Other Ingredients:Natural mixed berry flavor, xylitol, citric acid, silicon dioxide and stevia extract.

Contains no added starch, salt, wheat, gluten, corn, coloring, dairy products, or preservatives.

Keep container tightly closed in a cool, dry and dark place. Keep out of reach of children.

Recommended Intake

For relief from a urinary tract infection, repeat four to five (4-5) times per day.

For prevention of a urinary tract infection, drink once a day.

Description: D-Mannose is a naturally occuring simple sugar, closely related to glucose. Clinical studies have demonstrated its ability to prevent E. Coli bacteria from adhering to the inner walls of the bladder, potentially reducing the incidence and severity of urinary tract infections. D-Mannose Powder PLUS combines d-Mannose with Cranberry extract to enhance its effectiveness.

PLEASE NOTE: These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.

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By clicking on the following "Shopping Cart" buttons you are NOT obliged to purchase anything online. Even if you complete a transaction, you can always CANCEL it within 12 hours.

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Uribiotic Formula: A Broad-Spectrum Herbal Antibiotic

Over the years, at Full of Health, we have learned that urinary tract and/or prostate infections can be addressed naturally. With the help of antibacterial and anti-inflammatory herbs, nutrients and phytonutrients, it is possible to get through both acute and chronic infections by:

• disinfecting the urinary tract (an antimicrobial action)
• inhibiting and preventing inflammation
• enhancing the growth of some forms of beneficial bacteria within the body such as Bifidobacteria bifidus and Lactobacillus acidophilus
• destroying some forms of detrimental fungi such as Candida albicans and Candida krusei.

By preventing bacterial cell division and breaking down the walls and cytoplasm of bacteria (in a similar fashion to some types of pharmaceutical antibiotics), Uribiotic Formula helps to inhibit the growth (or kill) many types of detrimental pathogenic bacteria including:

• Actinomyces naeslundii
• Bacillus anthracis (on the basis of its known ability to kill other species of Bacillus)
• Bacillus alvert
• Bacillus cereus
• Bacillus subtilis
• Brucella abortus
• Campylobacter jejuni
• Chlamydia pneumoniae
• Chlamydia trachomatis
• Clostridium species ( botulinum, tetani)
• Cornybacterium diphtheriae
• Enterococcus species (faecalis)
• Eschericia coli (E. coli)
• Helicobacter pylori
• Haemophilus influenzae
• Klebsiella pneumoniae
• Legionella pneumoniae
• Listeria monocytogenes
• Moraxella catarrhalis
• Mycobacterium smegmatis
• Mycobacterium tuberculosis
• Neisseria gonorrhoeae
• Neisseria memingitidis
• Pasteurella septica
• Pneumocystis carinii
• Propionibacterium acnes
• Proteus mirabilis
• Proteus vulgaris
• Pseudomonas aeruginosa*
• Pseudomonas cepacia
• Salmonella enteridis
• Salmonella enteritidis
• Salmonella choleraesuis
• Salmonella paratyphi A
• Salmonella typhimurium
• Serratia marcescens
• Shigella dysenteriae
• Shigella flexneri
• Shigella sonnei
• Staphylococcus aureus (responsible for "Golden Staph")**
• Streptococcus faecalis
• Streptococcus mutans (alpha-hemolytic Streptococcus)
• Streptococcus pneumoniae (alpha-hemolytic Streptococcus)
• Streptococcus pyogenes (beta-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
• Streptococcus sanguis (alpha-hemolytic Streptococcus)
• Streptococcus viridans (alpha-hemolytic Streptococcus)
• Streptomyces species
• Treponema pallidum
• Vancomycin-Resistant Enterococcus (VRE)

* PLEASE NOTE: Pseudomonas aeruginosa is the third leading cause of hospital-acquired urinary tract infections, accounting for approximately 12 percent of all infections of this type. They are usually related to urinary tract catheterization, instrumentation or surgery.

Pseudomonas aeruginosa appears to be among the most adherent of common urinary pathogens to the bladder uroepithelium. An infection can occur via an ascending or descending route.

Pseudomonas aeruginosa can also invade the bloodstream from the urinary tract. This route is the source of approximately 40 percent of Pseudomonas aeruginosa infections.

April 17, 2009: Thanks, Andrew, for your advice and support with my Pseudomonas [aeruginosa] bladder infection with your amazing product Uribiotic which stopped the infection and kept it away. I've suffered from UTIs for 18 years since my spinal cord injury and now I'm infection free. JASON C. Great Britain

** PLEASE NOTE: In case of Staphylococcus aureus infections, Uribiotic Formula can be a part of a combined antibiotic therapy as it may enhance the effectiveness of pharmaceutical antibiotics for the UTI treatment.

Uribiotic Formula: An Immune Booster

An immune-boosting Uribiotic Formula helps to increase the natural safeguards - bodily defense systems that protect the urinary tract against pathogenic, infection-causing bacteria, such as:

• the flow of urine which functions as an antiseptic, helping to wash potentially harmful bacteria out of the body during normal urination. (Urine is normally sterile, that is, free of bacteria, viruses, and fungi!)
• the ureters (muscular ducts that propel urine from the kidneys to the urinary bladder) and the bladder
• the immune defenses and antibacterial substances in the mucous lining of the bladder
• the bladder lining cells that, literally, sacrifice themselves and self-destruct to fight off detrimental bacteria (a process called apoptosis). In so doing, they fall away from the lining, carrying the bacteria with them. This process, suggested by some interesting research, eliminates about 90% of the E. coli
• the vagina which is colonized - in normal fertile women - by lactobacilli, beneficial micro-organisms that maintain a highly acidic environment (low pH). Lactobacilli also produce hydrogen peroxide, which helps eliminate bacteria and reduces the ability of E. coli to adhere to vaginal cells
• the so-called human beta-defensin-1 (HBD-1) which fights E. coli within the female urinary and reproductive tracts -.a possible natural antibiotic identified by some researchers
• the antibacterial actions of some secretions of the prostate gland probably for why men are less likely than women to develop urinary tract infection.

Uribiotic Formula: Health Benefits Summary

It is so embarrassing having consult your doctor for the same reason (another infection!) and need to take another round of antibiotics.

The truth is, however, that urinatry tract and/or prostate infections CAN be successully remedied and prevented without multiple rounds of prescription medications (antibiotics).

Health benefits of our proprietary Uribiotic Formula - a synergistic blend of 45 nutrients, phytonutrients (plant nutrients) and herbs thoroughly researched and put to the test - include:

• anti-inflammatory
• antibacterial
• antifungal
• antiviral
• antiparasitic
• antioxidant
• anti-edematous
• antitumor.

Uribiotic® Formula Advanced Urinary Tract Prostate Support * 90 Vegetarian Capsules Serving Size: 3 Capsules     Servings Per Bottle: 30 SUPPLEMENT FACTS:   Amount Per Serving 45 Phytonutrients and Nutrients
1. Vitamin A (All Trans Retinyl Palmitate)	1,000 IU
2. Vitaminc C (Calcium Ascorbate)	60 mg
3. Vitamin E (d-Alpha-Tocopherol Succinate)	25 IU
4. Biotin	300 mcg
5. Magnesium (Citrate)	150 mg
6. Zinc (Monomethionine)	25 mg
7-45. PROPRIETARY BLEND:
Golden Rod (Solidago virgaurea) (Aerial Parts), Cranberry Powder (Vaccinium macrocarpon) (90% Cranberry Solids), Saw Palmetto Berry Powder (STD 25% Fatty Acids) (Serenoa repens), Uva Ursi Leaf (Standardized to 10%-20% Arbutin) (Arctostaphylos uva-ursi), Oregano Leaf (10% Thymol) (Origanum vulgare), Echinacea STD (70% Echinacea angustifolia, 30% Echinacea purpurea) (Aerial Parts), Berberin (Barberry Root Extract 4:1) (Berberis aristata), Goldenseal Root (Standardized to 9% Alkaloids, including 5% Hydrastine) (Hydrastis canadensis), Nettle Root (Urtica dioica), Propolis 2:1, Garlic Bulb Standardized (Allium sativum), Grapefruit Seed Extract, Olive Leaf Extract (Olea europaea), Buchu Leaf Extract (Barosma betulina), Corn Silk (Zea mays), Lactoferrin, Marshmallow Root (Althaea officinalis), Meadowsweet Leaf (Filipendula ulmaria), Pau D'Arco (Tabebuia impetiginosa) (Bark), Couch Grass (Agrophyron repens), Horsetail Grass Standardized (Equisetum arvense), Asparagus Shoot (Asparagus officinalis), Beta-Sitosterol, Black Walnut Hulls (Juglans Nigra), Clove Fruit (Syzygium aromaticum), Quercetin, Rutin, Yarrow Flower (Achillea millefolim), Cayenne Berry (Capsicum annum), Astragalus Root 0.3% Extract (Astragalus membranaceus), Eleutherococcus senticosus (Standardized to 0.8% Eleutherosides) (Root), Gentian Powder (Gentiana lutea) (Root), Silymarin Extract Standardized (from Milk Thistle Seed), Bromelain, Chlorophyll (as Sodium Copper Chlorophyllin), Papain, Vinpocetine, Trans-resveratrol (from Grape Vine Shoot extract), Lycopene Extract.	986.5 mg
Other ingredients: Hydroxypropylmethylcellulose (vegetable capsule), microcrystalline cellulose, vegetable stearate and silica.
This product is manufactured in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.	QUALITY & SAFETY ASSURANCE
Take 3 capsules 3 times daily in between meals, each time with 4 ounces (½ cup) of purified lukewarm water, or as recommended by a qualified healthcare professional.	DIRECTIONS
If you are under a physician’s care or taking medication, or if you are pregnant or nursing, consult your healthcare practitioner before using this product.	CAUTION
This product does not contain MSG, wheat, gluten, soy protein, fish, shellfish, milk/dairy, corn, egg, nuts, sugar, salt, starch, artificial coloring, preservatives or flavoring.	PREMIUM PURITY
FULL OF HEALTH, INC. Since 1996 Uribiotic® Formula: Advanced Urinary Tract Support * * This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Full of Health and Uribiotic are registered trademarks of Full of Health, Inc.

Thousands of people around the world have proven the efficacy of this approach. And what is most important, there has not been a single reported harm done by taking the Uribiotic Formula.

Healing Properties

Uribiotic Formula can cause the almost instant disappearance of the painful burning sensation when urinating the need for frequent urination the inability to empty the bladder completely even though you have the urge. Uribiotic Formula can help you eliminate: the harmful bacteria from the inside of the urinary tract and without disrupting the normal body functions. Uribiotic Formula can help you prevent and remedy: both acute and repeated (chronic) urinary tract and/or prostate infections, and the need and dependence on antibiotics.

Recommended Intake

Upon the first signs of urinary tract infection, begin taking 3 capsules of the Uribiotic Formula 3 times daily (morning, noon, afternoon) 20-30 minutes apart from having food, each time with ½ glass of purified lukewarm water.

Also do your best and try to sip lots of water throughout the day.

PLEASE NOTE: If necessary, Uribiotic Formula can be a part of a combined antibiotic therapy as it may enhance the effectiveness of pharmaceutical antibiotics for the treatment of urinary tract infections (UTIs), especially in case of Staphylococcus aureus infections.

First Signs of Relief Within 12-48 Hours

You should experience the first signs of relief within 12-48 hours after you begin taking the Uribiotic Formula. The symptoms should be cleared completely within 10 days, provided you will keep taking the Uribiotic Formula consistently without skipping doses.

However, the results may vary from person to person depending on the diagnosis, degree of UTI, age, sex and other existing health conditions.

Our Clients Write to Us:

Friday, July 14, 2007: Problem solved! The infection is GONE! I just thought you might want to know this in case you get any customers notifying you that URIBIOTIC doesn't seem to be working. I love your product and continue to rave and refer anyone I talk to about UTIs to your website. THANK YOU FOR CREATING THIS PRODUCT!!! Katie B. Denver, Colorado

No Side Effects

Formulated with care by a master formulator and manufactured according to the highest standards *, this unique synergistic combination can help you deal with your bladder, prostate and/or even kidney infection:

• safely
• effectively, and
• with no side effects.

* QUALITY & SAFETY ASSURANCE: Uribiotic Formula is manufactured in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.

Cautions and Contraindications

Sexual System:
Uribiotic Formula should not be consumed during pregnancy as it can cause contractions of the uterus due to presence of Goldenseal, Vinpocetine and hydroquinone (via arbutin present in Uva Ursi/Bearberry).

Cardiovascular System:
Uribiotic Formula should be consumed with caution by patients with severe hypertension (high blood pressure) due to the presence of Nettle root as it may further raise blood pressure in some people. However, Olive Leaf Extract, Rutin and Siberian Ginseng (Eleutherococcus senticosus) present in the Uribiotic Formula may actually help lower blood pressure in hypertension patients.

Pharmaceutical Drugs:
Uribiotic Formula should be consumed with caution by patients on a high dose of warfarin (blood thinner) due to the presence of garlic which may potentiate the anticoagulant effects of warfarin. (Reference: Fugh-Berman, A. Herb-drug interactions. Lancet. 355(9198):134-138, 2000).

PLEASE NOTE: When acute nephritis (kidney infection) is present - accompanied by high fever along with sudden retention of urine (a painful urge to pass urine but the inability to do so) - have your condition assessed immediately by your physician.

Do Not Stop!

Although symptoms-free, please do NOT stop taking the Uribiotic Formula and continue to use it until the botle is empty (up to 10 days).

If you are prone to repeated (chronic) urinary tract and/or prostate infections, for the first few months, keep an extra bottle of the Uribiotic Formula on hand, and use it immediately at the first signs of infection for the minimum of three (3) consecutive days.

In time, however, you will notice that the frequency of your urinary tract and/or prostate infections begins to seize, making the further use of the Uribiotic Formula - with some possible exceptions - unnecessary or occasional only.

Simple and Astonishingly Effective

Our proprietary Uribiotic Formula is so simple and astonishingly effective that it continues to amaze even the most skeptical people.

For this reason, we have decided to go worldwide and share our experience with the public on the Internet to help people around the world to remedy bladder, prostate or even kidney infection.

So far, we have introduced our proprietary Uribiotic Formula to our clients and customers in 27 countries: the United States, Australia, the United Kingdom, South Africa, New Zealand, Germany, Belgium, Mexico, Italy, Singapore, France, Russia, Croatia, Poland, Portugal, Denmark, United Arab Emirates, Hong Kong, St. Lucia (West Indies), Norway, Saudi Arabia, Turkey, Slovenia, Greece, Qatar, Jordan and Israel.

With no doubt this superb supplement can be of great benefit to you. You have nothing to lose - and lots to gain. And if necessary, it can be a part of a combined antibiotic therapy as Uribiotic Formula may even enhance the effectiveness of standard pharmaceutical antibiotics for the treatment of urinary tract infections (UTIs), especially in case of Staphylococcus aureus infections.

Therapeutic and Preventive Intake: Directions

With possible variations from person to person, the suggested intake of the Uribiotic Formula - depending on the diagnosis, degree of UTI, sex, age and other existing health conditions - can be described as follows: I. Acute UTI: In case of first signs of discomfort (slight burning sensation when urinating, frequent urination and/or inability to empty bladder completely) you need to take: 3 capsules 3 times daily; therefore, for full benefits, at least 1 bottle of the Uribiotic Formula is needed (an initial 10-day therapeutic intake). In case persistent signs of UTI (painful burning sensation when urinating, frequent urination at night and/or inability to empty bladder completely) you need to take: 3 capsules 3 times daily; therefore, for full benefits, 2 bottles of the Uribiotic Formula are needed (an extended 20-day therapeutic and prophylactic intake). II. Chronic/Repeated UTI: In case of recurrent, repeated UTIs (all the above symptoms along with the need and dependence on antibiotics) it is necessary to take: 3 capsules 3 times daily; therefore, for full benefits, 3 bottles of the Uribiotic Formula are needed (an intensive 30-day therapeutic and prophylactic intake) DIRECTIONS: Take the capsules throughout the day in between meals (on an empty stomach), preferably before 6 pm, each time with ½ glass of purified lukewarm water. PLEASE NOTE: After all symptoms have disappeared, in order to restore the urinary tract’s normal pH and, thus, prevent recurring UTIs, taking one (1) capsule of the Uribiotic Formula three (3) times daily for at least ten (10) consecutive days is highly recommended. ADDITIONAL RECOMMENDATION: In order to fully exert the therapeutic, protective and preventive (prophylactic) effects of the Uribiotic Formula, it might be taken along with probiotics, especially Probiotic LGG Plus. CAUTIONS: Uribiotic Formula should not be used by pregnant women. Also patients with severe hypertension (high blood pressure) should take it in caution. However, Olive Leaf Extract, Rutin and Siberian Ginseng (Eleutherococcus senticosus) present in the Uribiotic Formula may actually help lower blood pressure in hypertension patients). It should also be taken with caution by patients on a high dose of warfarin (blood thinner) due to the presence of garlic which may potentiate the anticoagulant effects of warfarin. (Reference: Fugh-Berman, A. Herb-drug interactions. Lancet. 355(9198):134-138, 2000). PLEASE NOTE: When acute nephritis (kidney infection) is present - accompanied by high fever along with sudden retention of urine (a painful urge to pass urine but the inability to do so) - have your condition assessed immediately by your physician. ATTENTION: Male Adults with BPH: Although we have found the Uribiotic Formula effective in both women and men, the latter - besides bladder infections - quite offten suffer from undiagnosed prostate infection (prostatitis) and/or benign prostatic hyperplasia (BPH), a non-cancerous swelling of the prostate gland. If this is a case, for full benefits we recommend taking the Uribiotic Formula along with an exceptional supplement: European DP Extract.

Secure Online Orders

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 Uribiotic Orders: United States and Worldwide 
 (Except in Canada) 

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Security and Confidentiality:
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If you do not feel comfortable placing your order online, please call us:

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You can also fax your order:

• 1. 705. 876. 8592 (US/Can).

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Bladder Infections in Paraplegia (SCI)

Neurological conditions like paraplegia, a spinal cord injury, also called spinal cord impairment (SCI), usually result in a neurogenic bladder - an unstable or atonic bladder (with no muscle tone).

People with spinal cord injuries have lost, partial or complete, control over their bladder and sphincter due to the compromised nerve receptors that are responsible for:

• contracting and relaxing the muscles of the bladder and the sphincter, and
• registering feelings of pressure or release.

Due to this condition, most paraplegics are exposed to the regular use of catheters and drugs. (The more traditional cap and bag, with continual drainage, is falling from favor even though it is a safer system).

However, catheters often increase the risk of the urinary tract injuries and repeated bladder infections - a common problem in people with spinal cord impairment.

Exposed to repeated or long-term courses of antibiotics, in time, they also develop resistance to drugs what makes maintaining healthy urinary tract for them even more difficult.

Contrary to a popular belief and common medical practice, people with spinal cord injuries or spinal cord impairment do NOT have to:

• suffer from chronic bladder-kidney infections and
• be exposed to vicious antibiotics.

It is our clinical experience that paraplegics, expecially those who use catheters, can successfully remedy, and most importantly, prevent bladder-kidney infections with the help of our proprietary UTI Uribiotic Unisex Formula.

Therefore, you, or someone you know or hold dear, who suffers from spinal cord injury, should give this superb herbal blend serious consideration.

Our Clients with SCI Write to Us: Testimonials

December 14, 2007: As a paraplegic for almost 14 years, I was almost constantly on antibiotics due to chronic bladder infection. However, being afraid of possible side effects, for many years I was reluctant to consider any natural alternatives. I was afraid of getting diarrhea or constipation. These are the worst - a real disaster! But after successful experience with D-Mannose, I started looking for other natural means to solve my problem. And I was pleasantly surprised by lack of any adverse reactions to URIBIOTIC, which I introduced to my system very cautiously. Two weeks later, my urine culture showed NO E. coli. Burning went away in a few days. I'm pleased to report such great results. Barret D. Minnesota

April 17, 2009: Thanks, Andrew, for your advice and support with my Pseudomonas [aeruginosa] bladder infection with your amazing product Uribiotic which stopped the infection and kept it away. I've suffered from UTIs for 18 years since my spinal cord injury and now I'm infection free. JASON C. Great Britain

If Your Infection Persists

On rare occasions the Uribiotic Formula alone does not seem to be enough, especially when the infection has already spread into the entire urinary tract, the following remedies should be be considered:

• D-Mannose Powder PLUS
• Pure Essential Oil of Wild Oregano
• Probiotic LGG Plus.

ATTENTION: Male Adults with BPH

Although we have found the Uribiotic Formula effective in both women and men, the latter - besides bladder infections - quite offten suffer from undiagnosed prostate infection (prostatitis) and/or benign prostatic hyperplasia (BPH), a non-cancerous swelling of the prostate gland.

If this is a case, for full benefits we recommend taking the Uribiotic Formula along with another exceptional supplement, namely:

• European DP Extract: Enlarged Prostate (BPH) Remedy.

Advanced Urinary Tract & Prostate Support: Our Program

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	UTI Uribiotic Formula: BLADDER Infection Herbal Remedy
	European DP Extract: Enlarged Prostate (BPH) Remedy
	D-Mannose Pure Powder: UTI Natural Remedy
	Pure Essential Oil of Wild Oregano: UTI Herbal Antimicrobial Remedy
	Probiotic LGG Plus: UTI Mixed Beneficial Bacteria
	The Low-Grain, Low-Sugar Delight: UTI Cookbook
	FREE e-Pamphlet: Say NO! to Urinary Bladder Infection

NEED HELP OR ADVICE?
Contact us by or by phone: 1. 705. 876. 9357 (US/Can)
Mon-Fri: 10:00 am-3:00 pm EST (Weekends & Holidays Excluded)

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© 2003-2009 Remedy-Bladder-Infection.com: Stop Urinary Bladder Infection with UTI Uribiotic Unisex Herbal Formula. The Natural UTI Cure, Treatment & Prevention. Alternative, herbal and nutritional treatment for cystitis, urethritis, urethral syndrome, prostatitis. Prevent and remedy urinary tract infection (UTI) without antibiotics. The information provided herein on bladder-prostate infection is a general overview on this topic and may not apply to everyone, therefore, it should not be used for diagnosis or treatment of any medical condition. While reasonable effort has been made to ensure the accuracy of the information on the natural bladder prostate infection treatment, Full of Health Inc. assumes no responsibility for errors or omissions, or for damages resulting from use of the bladder prostate infection information herein.

URIBIOTIC and FULL OF HEALTH are registered trademarks of Full of Health, Inc.

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