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D-Mannose Powder PLUS: The Natural Alternative to Antibiotics
D-mannose, a simple sugar and close cousin of glucose, can cure more than 90 percent of all bladder infections within 1 to 2 days. Even more remarkably, D-mannose accomplishes this feat without killing a single bacterium! (Exactly how does this it will be explained later). Suffice it to say that, because it gets rid of bladder infection-causing bacteria without committing "bactericide," people who use it suffer none of the unwanted side effects of antibiotics:
In fact, D-mannose has no adverse side effects of any kind.
It Tastes Good!
It Is Effective and Safe!
It Is Suitable for Children
It Is Just As Effective As Antibiotics Moreover, nearly 15 years of clinical experience have shown that it is just about as effective at curing bladder infections as antibiotic drugs.
It Has No Known Drawbacks Unlike virtually any conventional medication, and many natural or "alternative" treatments as well, D-mannose has no known drawbacks. E. Coli Bacterial Infections Bladder infection is a bacterial infection (caused by the bacteria E. coli over 90 percent of the time) that affects the inside lining tissue of the urinary system (or tract). The urinary tract reacts to a bacterial infection in much the same way that the upper respiratory system reacts to a cold virus. The tissues become inflamed, irritated, and swollen. Just as it's hard to breathe through swollen and inflamed nasal passages, swollen and inflamed urinary ducts can partially obstruct normal flow, making it painful and difficult to pass urine.
Built-In Safeguards Bugs that do make their way into a healthy urinary tract are likely to find an inhospitable acidic environment (pH <5.5). Bugs are also subject to attack by the body's immune defenses. (Adult men have the added protection of a specific bacterial growth inhibitor squirted directly into the urinary system by their prostate gland.) Even if microorganisms manage to overcome these considerable obstacles, they would typically be flushed out with the normal flow of urine. So effective are these natural antibacterial defenses that in a study in which bacteria were instilled directly into the bladders of guinea pigs, simple urination expelled 99.9 percent of the bugs. Despite all these built-in safeguards; each year millions of people, overwhelmingly women, still develop bladder infections.
Urethritis
Cystitis
Nephritis The E. coli that cause most bladder infections are among the most common friendly bacteria in the gastrointestinal (GI) tract, where they aid digestion, produce a few vitamins, and in general, behave themselves without bothering us. However, when E. coli and other bugs exit the lower GI tract, they may gain entry to the urinary tract via the urethra, where they may attach to the internal lining of the bladder, multiply, and spread.
Other Infectious Bacteria
Unlike E. coli, these bugs tend to be transmitted via sexual contact and rarely cause the more serious bladder and kidney infections. PLEASE NOTE: Chlamydia, Mycoplasma and N. gonorrhea infections do not respond to D-mannose treatment and and will probably require antibiotic treatment.
Non-E. Coli Bladder Infections
Still, all of these non-E. coli infections combined amount to no more than 10 percent of all bladder infections. D-Mannose: Bladder Infection Treatment Conventional Medicine When faced with a potentially pathogenic germ like E.coli, conventional, pharmaceutically based medicine typically confronts the problem by throwing the most potent poisons it can find at the bugs - antibiotics. While there's nothing essentially wrong with killing disease-causing bacteria, this approach does have some very serious drawbacks, as we have noted earlier. Happily, "bacteria-cide" is not the only possible avenue of attack.
More Natural Way At the tip of each fimbrium is a glycoprotein (a combination carbohydrate and protein) called a lectin that is programmed to bind to the first molecule of the sugar mannose that it encounters. It turns out that molecules of mannose (produced inside urinary tract lining cells) naturally dot the surfaces of these cells. Here they act as "receptors," inviting the fimbria of E. coli to attach, and allowing them to bind to the tissue in a tight, Velcro-like grip. If not for this attachment to the cell's mannose, any E. coli that had successfully ventured up the urethral river would be unable to stick to the slippery surface and would be washed right back out on the next tide of urination. D-Mannose: How Does It Work? Now imagine what would happen to E. coli in the urinary tract if those sweet little mannose molecules they crave were present not just on the surface of the epithelial cells but surrounding them in the urine as well. The E. coli couldn't turn around without bumping into D-mannose "just floating around" in the urine. Unable to resist the tasty bait they suddenly find themselves swimming in, they would latch onto the nearest mannose molecules, and happily sail off into the porcelain sunset. Those few E. coli left clinging to mannose molecules on cells then become easy prey for white blood cells and other agents of the immune system.
E. Coli Coated With D-Mannose Extracted in the form of D-mannose, a white crystal sugar similar to glucose, it can be easily dissolved in a liquid and swallowed. (Mannose can also be synthesized from other simple sugars.) When someone with bladder infection consumes a dose of D-mannose, the sugar is absorbed in the upper GI tract, but at a much slower rate than most other sugars. (For example, glucose is absorbed more than eight times faster.) Moreover, unlike other sugars, D-mannose is not readily converted to glycogen (and stored) in the liver, but instead passes directly into the bloodstream largely unchanged. As the D-mannose-laden blood passes through the kidneys, a considerable proportion of the sugar is extracted and added to the urine. The D-mannose-sweetened urine flows from the kidneys through the ureters to the bladder and on to the urethra, literally sugar-coating any free-floating E. coli it might encounter, so they can't stick to cells any more. It also unsticks most of the E. coli already "Velcro-ed" to the inner surface of the bladder and urinary tract, ultimately flushing them all down the drain.
It Is Scientifically Proven Second, literally tens of thousands of women working with natural medicine doctors have successfully applied this science to their own bladder infections.
Therapeutic Value of D-Mannose
Laboratory Studies In another study, administering a mannose-like substance (niethyl a-D-mannopyranoside) to E. coli-infected mice led to a 90 percent reduction in bacterial attachment to the urinary tract. Research in humans shows that ingesting D-mannose significantly elevates blood mannose levels, a prerequisite if urinary levels are to rise.
Epidemiological Evidence
For example, in one case, a 5-year-old girl had almost continuous bladder infections for her entire life that had failed to respond to every antibiotic therapy her physicians tried (72 doctors in all!). At the end of their rope, her doctors were now considering a kidney transplant, since her kidneys were starting to fail due to years of chronic infection. Since urine culture showed her bladder infection was due to E. coli, she was started on D-mannose (1 tsp in a glass of water every 2-3 hours). Within 48 hours, her infection had vanished, and her kidneys were saved!
"Honeymoon Cystitis"
If a urine culture shows the presence of E. coli, taking D-mannose, 1 teaspoon 1 hour prior to intercourse, will mostly likely completely eliminate further infections.
Recurrent Bladder Infections
Single Bladder Infections
In over 90 percent of such cases, 1 teaspoon of D-mannose every 2 to 3 hours usually clears the infection in 1 to 3 days. D-Mannose: Try It First > Ninety percent of the time, bladder infection is caused by E. coli and will respond to D-mannose Plus treatment with significant symptom reduction within 24 hours. PLEASE NOTE: Even though symptoms are improved within 24 hours, D-mannose Plus should be continued for 2 to 3 days after the last symptom is gone, just to "make sure."
A Word of Caution D-Mannose: Supplement Facts Serving Size: 1 Level Teaspoon (4.7 grams) Servings Per Container: 30 Amount Per Serving:
Other Ingredients: Natural mixed berry flavor, xylitol, citric acid and sucralose. Contains no added starch, salt, wheat, gluten, corn, coloring, dairy products or preservatives. Keep container tightly closed in a cool, dry and dark place. Keep out of reach of children. Recommended Intake Directions: Mix 1 level teastoon (4.7 grams) in 4 to 6-ounces of purified, cold water. For relief from a urinary tract infection, repeat four to five (4-5) times per day. For prevention of a urinary tract infection, drink once a day. Description: D-Mannose is a naturally occuring simple sugar, closely related to glucose. Clinical studies have demonstrated its ability to prevent E. Coli bacteria from adhering to the inner walls of the bladder, potentially reducing the incidence and severity of urinary tract infections. D-Mannose Powder Plus combines d-Mannose with Cranberry extract to enhance its effectiveness. PLEASE NOTE: These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease. Effective in Paraplegic Bladder Infections Neurological conditions like paraplegia, a spinal cord injury, also called spinal cord impairment (SCI), usually result in neurogenic bladder - an unstable or atonic bladder, with no muscle tone. People with spinal cord injuries have lost, partial or complete, control over their bladder and sphincter due to the compromised nerve receptors that are responsible for:
Due to this condition, most paraplegics are exposed to the regular use of catheters and drugs. (The more traditional cap and bag, with continual drainage, is falling from favor even though it is a safer system). However, catheters often increase the risk of the urinary tract injuries and repeated bladder infections - a common problem in people with spinal cord impairment. Exposed to repeated or long-term courses of antibiotics, in time, they also develop resistance to drugs what makes maintaining healthy urinary tract for them even more difficult. However, contrary to a popular belief and common medical practice, people with spinal cord injuries or spinal cord impairment:
It is our clinical experience that paraplegics, especially those who use catheters, can successfully remedy, and most importantly, prevent bladder infections with the help of supplemental D-Mannose. Therefore, you, or someone you know or hold dear, who suffers from paraplegia, should give this natural E. coli fighter serious consideration. If Your Infection Persists Not ALL urinary tract infections are caused by E.coli. Therefore, if you try a course of D-Mannose and infection persists, it is likely NOT caused by E. coli bacteria but by some other pathogen or pathogens, like Chlamydia, Mycoplasma, or - more likely - Proteus or Staphylococcus aureus ("Staph"). In that case, don't just keep going on with the supplement in hopes that it will eventually "kick in." Discontinue the use of D-Mannose. If this is a non-E. Coli infection caused by Proteus or "Staph" consider using herbal remedies, such as: Urinalysis Test A sample of your urine needs be tested for pus and bacteria. You will be asked to give a "clean catch" urine sample by washing the genital area and collecting a "midstream" sample of urine in a sterile container. (This method of collecting urine helps prevent bacteria around the genital area from getting into the sample and confusing the test results.) Usually, the sample is sent to a laboratory, although some doctors' offices are equipped to do the testing. In the urinalysis test, the urine is examined for white and red blood cells and bacteria. The bacteria are grown in a culture and tested - usually, against different antibiotics - to see which drug best destroys the bacteria. This last step is called a sensitivity test. However, some microbes, like Chlamydia and Mycoplasma, can only be detected with special bacterial cultures. These infections are suspected when you have symptoms of an infection and pus in the urine, but a standard culture fails to grow any bacteria. Selected References
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