The Natural Alternative to Antibiotics:
D-Mannose Pure Powder
Effective and Safe In Pregnancy, Suitable For Children
Short Story
A few strains of E. coli bacteria that cause most lower urinary tract
infections - urethritis and cystitis - are like Velcro. They have tiny
"grappling hooks" (pili) that allow them to bind to "loops" (certain
receptors) on the cells of the urinary tract.
A key part of the structure of these "loops" are residues of the simple
sugar D-mannose. So when these bacteria are surrounded by high
levels of D-mannose, their "grappling hooks" become glommed up,
preventing them from adhering to the cells of the urinary tract. (It is
a separate, complementary mechanism to the anthocyanins in
cranberries).
Full Story
If E. coli bacteria get into the bladder (or the urethra), the
body has ways of fighting them off - including the obvious methods of
simply flushing them out with the urine.
However, these invading bacteria have evolved ways of anchoring
themselves to the cells of the urinary tract.
E. coli are able to take advantage of receptors naturally found
on the cells of the mucosal lining of the urinary tract. (These
receptors are like molecular "docking bays" for substances which the
cells need for their normal growth and development).
E. coli then, like pirates in an old movie, use "grappling
hooks", called type I pili, to first hook on to these receptors, and
then to invade the cell.
Once inside the cell, E. coli CAN live and reproduce in safety,
shielded from many of the body's defensive immune responses.
In fact, E. coli are so sophisticated that when the body detects
that cells have been infected and activates the cell suicide program to
destroy the bacteria, these bacteria can actually... flee the dying
host cell before it is flushed out, and look for... new cells to
invade!
D-Mannose - Molecular "Chaff"
Pathogenic E. coli bacteria's pili "grappling hooks" are
composed of long, fibrous chains of a molecular "glue" called
adhesion.
The effective binding of these adhesion molecules depends on the
chemical attraction that exists between them and the residues of a
simple carbohydrate called D-mannose on the cell surface
receptors of the urinary tract host cells.
The chemical attraction between E. coli adhesions and
D-mannose is their strength - but it also provides a point of
vulnerability.
Therefore, if you can interfere with the binding of adhesions to the
D-mannose residues in the receptors of your urinary tract cells,
then you can also prevent E. coli from getting a foothold for
adherence and infection.
One way to do this - long known to work in a test tube - is by using
D-mannose itself. When isolated urinary tract cells are bathed
in D-Mannose, it acts as a molecular "chaff."
The E. coli's bacterial adhesions bind to the D-mannose
in their environment instead of to the D-mannose residues on the
cells.
This gums up their pili and prevents them from hooking onto urinary
tract cells.
Clinical Application of D-Mannose
It was discovered in the late 1980s that a small amount of
D-mannose is present in the urine normally, apparently acting as
a defensive mechanism against pathogenic bacteria.
When D-mannose is taken as a supplement, much more of the
carbohydrate passes through the urinary tract, therefore, strengthening
this natural defense.
Many of our clients and customers have been reporting the successful
results in using supplemental D-Mannose Pure Powder to rid
themselves of bladder infection.
Even those who had remained infected after having been subjected to a
wide range of potent, side-effect-inducing antibiotics have
successfully rid themselves of chronic or acute infections using
D-Mannose Pure Powder.
The feedback is uniformly excellent from urinary tract infection
sufferers and their caregivers alike.
Try D-Mannose First
Perhaps the best available evidence, though, comes from the experience
of people who have used it. Natural medicine-oriented physicians have
been recommending D-mannose to their patients with urinary tract
infections since the mid-1980s with great success.
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It Is Effective and Safe, Even in Pregnancy
Because it is so effective and so benign, women (even pregnant women)
who are susceptible to recurrent bladder infections, can safely take
D-mannose as a preventive measure to head off future
attacks.
It Is Suitable for Children
D-mannose is also ideally suited for children with bladder
infections. Because it tastes so good (it is a sugar, after all!),
children actually enjoy taking it. |
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It Is Effective in "Honeymoon Cystitis"
For example, D-mannose can be very effective in cases of
"honeymoon cystitis." It's not uncommon for women to avoid sex because
they get a bladder infection nearly "every time" they have
intercourse.
If a urine culture shows the presence of E. coli, taking
D-mannose, 1 teaspoon 1 hour prior to intercourse-will mostly
likely completely eliminate further infections.
It Helps Prevent Repeated Bladder Infections
Physicians experienced with D-mannose report that women prone to
very frequent recurrent bladder infections that are not
necessarily related to sexual intercourse can also often benefit from
taking D-mannose preventively. To save expense, some women have
been able to "taper down" their dosage and dose frequency.
It Is Effective in Acute Bladder Infections
By far the most frequent success with D-mannose has been
achieved by the thousands of women who have suffered single
(non-recurrent) episodes of bladder infection.
In over 90 percent of such cases, 1 teaspoon of D-mannose every
2 to 3 hours usually clears the infection in 1 to 3 days.
Ninety percent of the time, bladder infection which is caused by E.
coli, will respond to D-mannose treatment with significant
symptom reduction within 24 hours.
PLEASE NOTE: Even though symptoms are improved within 24 hours,
D-mannose should be continued for 2 to 3 days after the last
symptom is gone, just to "make sure."
Recommended Dosage
-
Take ½ - 1 teaspoon (~1.1 to 2.5 grams) of
D-Mannose (Glucose Steroisomer) in purified water, every 3-4
waking hours.
Discussion:
D-Mannose is a simple carbohydrate similar in structure to
glucose. Some unfriendly bacteria have lectins (adhesion molecules)
which bind to residues of mannose in the epithelium of the
urinary tract. Some clinical experience suggests that supplemental
D-Mannose acts as a molecular "chaff" to which bacteria bind,
preventing them from binding to urinary tract cells.
Purity: Assured by independent laboratory testing.
Contains NO wheat, gluten, nuts, dairy, soy, eggs, fish, or shellfish.
Source: Biological fermentation.
Cautions: None known.
Pregnancy-Nursing: No studies, believed safe. Consult with a
physician.
Great Success Rate
For the great majority of bladder infections - up to 90 percent -
D-Mannose Pure Powder offers:
- a safe, natural option, along with
- a simple, ingenious rationale
- no known side-effects, and
- a great reported success rate.
No wonder that so many of clients and customers in our practice have
been able to rid themselves of bladder infection within five (5)
days - after trying only one (1) course (20 servings) of
supplemental D-Mannose Pure Powder.
Our Clients Write to Us
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November 14, 2003
I was prescribed ciprofloxin, a very strong antibiotic with numerous
possible side effects, for an acute and painful kidney infection. After
7 days it did seem to stop the infection in my kidney, but not in my
urinary tract.
24 hours after completing my course of the antibiotic my order of
B.L.D.R. UriBiotic and D-Mannose arrived in the mail. I
was experiencing debilitating discomfort when I took my first dosage of
both products.
Within about 8 hours of beginning the natural remedy I began to
feel relief from my discomfort.
After 48 hours, my fequent urination stopped and I had no
discomfort.
I am continuing to take the remedies for another few days to make sure
all infection is gone.
I am convinced that if I had have taken the
remedies as soon as I noticed the symptoms of my infection, I would not
have had to take dangerous anti biotics.
I recomend these products highly, they work and they are safe.
Leo Downey
Rocky Mountain Buffalo Co.
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At Full of Health, we are sure this superb supplement will do as much
for you as it has done for them. If other people have benefited from
D-Mannose Pure Powder you can benefit as well.
Anyhow, is not a drug! D-Mannose is a nutritional supplement and
is naturally occuring in peaches, apples, berries and even produced in
the body. Therefore, it is safe and suitable for all ages, including
pregnant women and small children.
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If you don't feel comfortable placing your order over the Internet, please call us:
- 1. 705. 876. 9357 (US/Can).
Leave your name, phone number, and the best time to call you.
You can also fax your order to us:
- 1. 705. 876. 8592 (US/Can).
Effective in Paraplegic Bladder Infections
Neurological conditions like paraplegia, a spinal cord injury, also
called spinal cord impairment (SCI), usually result in neurogenic
bladder - an unstable or atomic bladder, with no muscle tone.
People with spinal cord injuries have lost, partial or complete,
control over their bladder and sphincter due to the compromised nerve
receptors that are responsible for:
- contracting and relaxing the muscles of the bladder and the
sphincter, and
- registering feelings of pressure or
release.
Due to this condition, most paraplegics are exposed to the regular use
of catheters and drugs. (The more traditional cap and bag, with
continual drainage, is falling from favor even though it is a safer
system).
However, catheters often increase the risk of the urinary tract
injuries and repeated bladder infections - a common problem in people
with spinal cord impairment.
Exposed to repeated or long-term courses of antibiotics, in time, they
also develop resistance to drugs what makes maintaining healthy urinary
tract for them even more difficult.
However, contrary to a popular belief and common medical practice,
people with spinal cord injuries or spinal cord impairment:
- do NOT have to suffer from chronic bladder infections and
- do NOT have to be exposed to vicious antibiotics.
It is our clinical experience that paraplegics, especially those who
use catheters, can successfully remedy, and most importantly, prevent
bladder infections with the help of supplemental D-Mannose Pure
Powder.
Therefore, you, or someone you know or hold dear, who suffers from
paraplegia, should give this natural alternative to antibiotics serious
consideration.
Our Clients Write To Us
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December 14, 2003:
As a paraplegic for almost 14 years, I was almost constantly on
antibiotics due to chronic bladder infection. However, being afraid of
possible side effects, for many years I was reluctant to consider any
natural alternatives.
I was afraid of getting diarrhea or constipation. These are the worst -
a real disaster! But after successful experience with D-Mannose,
I started looking for other natural means to solve my problem.
And I was pleasantly surprised by lack of any adverse reactions to
URIBIOTIC, which I introduced to my system very
cautiously.
Two weeks later, my urine culture showed no E. coli. Burning
went away in a few days. I'm pleased to report such great results.>
Barret D.
Minnesota
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If Your Infection Persists
Not ALL urinary tract infections are caused by E.coli.
Therefore, if you try a course of D-Mannose and infection
persists, it is likely NOT caused by E. coli bacteria but by
some other pathogen or pathogens, like Chlamydia,
Mycoplasma, or - more likely - Proteus or
Staphylococcus aureus ("Staph").
In that case, don't just keep going on with the supplement in hopes
that it will eventually "kick in." Discontinue the use of D-Mannose.
If this is a non-E. Coli infection caused by Proteus or "Staph"
consider using herbal remedies, such as:
Urinalysis Test
A sample of your urine needs be tested for pus and bacteria. You will
be asked to give a "clean catch" urine sample by washing the genital
area and collecting a "midstream" sample of urine in a sterile
container.
(This method of collecting urine helps prevent bacteria around the
genital area from getting into the sample and confusing the test
results.)
Usually, the sample is sent to a laboratory, although some doctors'
offices are equipped to do the testing.
In the urinalysis test, the urine is examined for white and red blood
cells and bacteria. The bacteria are grown in a culture and tested -
usually, against different antibiotics - to see which drug best
destroys the bacteria. This last step is called a sensitivity test.
However, some microbes, like Chlamydia and Mycoplasma,
can only be detected with special bacterial cultures.
These infections are suspected when you have symptoms of an infection
and pus in the urine, but a standard culture fails to grow any
bacteria.
Selected References
- Martinez JJ, Mulvey MA, Schilling JD, Pinkner JS, Hultgren SJ.
Type 1 pilus-mediated bacterial invasion of bladder epithelial
cells. EMBO J. 2000 Jun 15:19 (12):2803-12.
- Sauer FG, Mulvey MA, Schilling JD, Martinez JJ, Hultgren SJ.
Bacterial Pili: molecular mechanisms of pathogenesis. Curr Opin
Microbiol. 2000 Feb; 3 (1):65-72.
- Toyota S, Fukushi Y, Katoh S, Orikasa S, Suzuki Y.
Anti-bacterial defense of the urinary bladder. Role of mannose in
urine. Nippon Hinyokika Gakkai Zasshi. 1989 Dec; 80 (12):1816-23
- Wright JV. D-Mannose for bladder and kidney infections
Townsend Letter for Doctors and Patients. 1999 Jul;
192:96-8.
The Natural Urinary Tract Health Support:
NEED ADVICE?
Contact us by or by phone: 1. 705. 876. 9357 (US/Can)
Mon-Fri: 10:00 am-3:00 pm EST (Weekends & Holidays Excluded)
© 2003-2008 Remedy-Bladder-Infection.com: Stop Urinary Bladder Infection with UTI Uribiotic Unisex Herbal Formula. The Natural UTI Cure, Treatment and Prevention. D-Mannose Pure Powder. Alternative, herbal and nutritional treatment for cystitis, urethritis, urethral syndrome, prostate infection (prostatitis). Remedy and prevent urinary tract infection (UTI) without antibiotics. The information provided herein on bladder infection is a general overview on this topic and may not apply to everyone, therefore, it should not be used for diagnosis or treatment of any medical condition. While reasonable effort has been made to ensure the accuracy of the natural bladder infection treatment, Full of Health Inc. assumes no responsibility for errors or omissions, or for damages resulting from use of the bladder infection information herein.
URIBIOTIC is a registered trademark of Full of Health Inc.
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