Nearly all infections of the lower urinary tract and bladder are caused by a few strains of E. coli bacteria, called uropathogenic Escherichia coli (UPEC).

A variety of other Enterobacteriaceae and Gram-positive pathogens, includes:

• Staphylococcus saprophyticus - 5 to 15 per cent cases of urinary tract infections,
• Group B streptococcus - bacteria that can be found in the digestive tract, urinary tract, and genital area of adults,
• Chlamydia trachomatis - one of the most common cuases of bladder infection, especially urethritis,
• Mycoplasma hominis,
• Klebsiella pneumoniae,
• Enterococcus faecalis,
• Proteus mirabilis, or
• Pseudomonas aeruginosa.

They tend to remain limited to the urethra and reproductive system and, unlike E. coli, they are sexually transmitted.

Other possible causes of urinary tract infections include:

• yeast infection, especially if taking antibiotics for repeated infections
• allergies - mainly from foods,
• stress and anxiety,
• heavy metal toxicity, and
• poor kidney function.

Sexually Transmitted Chlamydia Infection

• the cervix,
• rectum, and
• eye.

Persons with chlamydia infections often have no symptoms. Consequently, they may transmit the infection to other people without knowing it. However, when the symptoms do occur, their type and severity will depend on the site of the infection and the person's response to it.

Women who do have symptoms of chlamydia infection may notice:

• an increased vaginal discharge,
• irritation of the area around the vagina, or
• burning pain with urination.

To diagnose chlamydia, a special test must be done by a health professional.

Chlamydia infection is easily treated with an antibiotic medication. However, if it is not detected and treated, chlamydia infection can lead to complications, such as pelvic inflammatory disease, a condition that signals the infection has spread to the uterus and fallopian tubes.

Symptoms of pelvic inflammatory disease include:

• lower abdominal pain,
• painful intercourse,
• irregular periods,
• spotting and
• fever.

This serious condition requires prompt medical attention.

In pregnant women, chlamydia infection can be passed on to their newborn children, where it can cause:

• eye infections and
• pneumonia.

E. Coli Bacterial Infection

A picture of E.coli bacteria. An undated file photo from the USDA

The bacteria, however, have multiple little hairs called cilia that function like little feet that allow them to climb from the skin around the vagina, up the urinary tube, into the bladder.

If UPEC (E. coli) get into the bladder or the urethra (tube that carries urine from the bladder), the body has ways of fighting them off - including the obvious methods of simply flushing them out with the urine. But these bacteria have evolved ways of anchoring themselves to the cells of the urinary tract.

The invading E. coli bacteria take advantage of receptors naturally found on the cells of the mucosal lining of the urinary tract. Receptors are like molecular "docking bays" for substances which the cells need for their normal growth and development.

Like pirates in an old movie, E. coli use "grappling hooks", called type I pili, to first hook on to these receptors, and then to invade the cell.

(These pathogenic "grappling hooks" are composed of long, fibrous chains of a molecular "glue" called adhesin).

Once inside the cell, E. coli can live and reproduce in safety, shielded from many of the body's defensive immune responses.

In fact, they are so sophisticated that when the body detects that cells have been infected and activates the cell suicide program to destroy the bacteria, UPEC can actually flee the dying host cell before it is flushed out, and look for new cells to invade!

Antibiotic Treatments: E. Coli Survival Rate

Bacteria E. coli are able to survive antibiotic treatment for bladder infections by reverting to an inactive state.

Within several days of antibiotic treatment, the number of bacteria reproducing drop to zero. Not all the bacteria are killed, though.

About 3 percent of the bacteria may be still present in a dormant state after treatment with ciprofloxacin (Cipro) and about 7 percent may linger after treatment with trimethoprim-sulfamethoxazole (Bactrim/Septra).

Even after a month of antibiotic exposure, about 10 million of the original 1 billion bacteria may remain.

Antibiotic treatment does not successfully kill all the bacteria participating in the infection and may, in fact, encourage many of the bacteria to persist in a resting state.

Therefore, current standard drug treatments for bladder infections are not adequate and this phenomenon may account for many of the repeat urinary tract infections.

E. Coli: New Antibiotic-Resistant Strain

The analyzed strain, resistant to trimethoprim-sulfamethoxazole, a popular two-drug combination, shows a pattern of resistance to multiple antibiotics and has genetic characteristics called "virulence factors" that increase its ability to infect the urinary tract.

Not much is known about how new strains of bacteria that infect the urinary tract arise and spread. There is also no evidence that the new strain of E. coli is causing any increase in kidney infections or other serious complications.

It could be that this organism has been around forever and has now acquired resistance to several antibiotics. It could have been introduced, perhaps through contaminated food.

E. Coli-Induced Repeated Bladder Infections

Most likely these are women over the age of 55 years or between the ages of 25 and 29.

Those women are likely to continue having urinary tract infecions, who have had three or more a year. Therefore, they can get another infection within 18 months of the last one, or even more requently.

One possible factor behind recurrent urinary tract infection may be the ability of bacteria to attach to cells lining the urinary tract.

The symptoms sometimes can be caused by chemical irritation such as bath additives and washing powders; they may disappear if toiletries and washing powder are changed.

Usually, the latest infection stems from a strain or type of bacteria that is different from the infection before it, indicating a separate infection.

Even when several urinary tract infections in a row are due to E. coli, slight differences in the bacteria indicate distinct infections.

However, some women have recurrent symptoms suggestive of urinary tract infection - but without infection being present. This condition is not serious but can be troublesome.

Chronic or recurrent urinary tract infections should be treated thoroughly because of the chance of kidney infection (pyelonephritis).

Prostate Gland Infection or Inflammation (Prostatitis)

Also repeated bladder infections can be associated with long-lasting or chronic prostatitis (CP) - the most common form of the disease, usually caused by detrimental bacteria.

Prostatitis affects 50 percent of men of all ages during their lifetimes. Its symptoms are similar to those of bladder infection.

Unfortunately, low-grade prostatitis is often missed on a doctor visit. Therefore, you may experience no symptoms or symptoms so sudden and severe that you have to seek emergency medical care.

However, if you are approaching age 50, you should also look for any of the following:

• a decrease in the force of your urine stream,
• difficulty in beginning urination,
• dribbling after you urinate, or a feeling that your bladder is not totally empty after you finish urinating.

These could also be symptoms of an enlarged prostate, a condition called benign prostatic hyperplasia (BPH) causing the buildup of urine in the bladder, which increases the likelihood that pathogenic bacteria will grow and trigger an infection.

Read more about prostate gland infection (prostatitis)...

Urinary Self-Defense Systems Against Bacteria

A number of defense systems - natural safeguards - that protect the urinary tract against infection-causing bacteria includes:

• the flow of urine which functions as an antiseptic, helping to wash potentially harmful bacteria out of the body during normal urination. (Urine is normally sterile, that is, free of bacteria, viruses, and fungi!);


• the ureters (tubes that carry urine from the kidneys to the bladder) and bladder which are structurally designed to prevent urine from backing up toward the kidneys;


• the immune defenses in both sexes continuously fights bacteria and other harmful micro-invaders. In addition, immune system defenses and antibacterial substances in the mucous lining of the bladder eliminate many organisms;


• the vagina which is colonized - in normal fertile women - by lactobacilli, beneficial micro-organisms that maintain a highly acidic environment (low pH). Acid is hostile to other bacteria. Lactobacilli also produce hydrogen peroxide, which helps eliminate bacteria and reduces the ability of E. coli - the major bacterial culprit in urinary tract infections - to adhere to vaginal cells;


• the bladder lining - when bacteria infect the cells that line the bladder they, literally, sacrifice themselves and self-destruct (a process called apoptosis). In so doing, they fall away from the lining, carrying the bacteria with them. This process, sugested by some interesting research, eliminates about 90% of the E. coli;


• a possible natural antibiotic - identified by some researchers - called human beta-defensin-1 (HBD-1) which fights E. coli within the female urinary and reproductive tracts.

Urinary Bladder Infection: Common Risk Factors

Being Female
The female urethra is shorter than the male's, allowing bacteria quick access to the bladder and this probably accounts for why women are more likely to develop urinary tract infection. In addition, a woman's urethral opening is near sources of bacteria from the anus and vagina.

Being Pregnant
Pregnant women, especially in the late stages of pregnancy, seem no more prone to an infection than other women; however, about 5 to 7 percent of pregnant women develop a urinary infection, probably due to previous infections before pregnancy, high sexual activity and diabetes, and also due to hormonal changes and shifts in the position of the urinary tract during pregnancy (the enlarged uterus continuously presses on the bladder).

PLEASE NOTE: Women who experience an untreated urinary tract infection during their third trimester of pregnancy are at greater risk of delivering a child who suffers from mental retardation or developmental delay.

Poor Hygiene
Genitals must be kept dry and clean! Less than careful hygiene, especially after developing loose stools or diarrhea, is one of the most frequent causes of repeated urinary tract infections.

It is very easy to contaminate one's fingers when wiping oneself with toilet paper, and if those contaminated fingers come anywhere close to the opening of the urethra, there is a high likelihood of infection in predisposed individuals.

Only white unscented toilet paper should be used as many women react to the dyes and chemicals in the other toilet papers.

Unbleached toilet paper would be even better to reduce:

• any possible chlorine exposure and
• the environmental contamination that comes from the bleaching process.

Sexual Position 'from Behind'
Some women find that they are liable to develop an infection if, during sexual intercourse, their partner enters their vagina 'from behind'. This is simply because in this position it is more likely that bacteria from around the anus may be pushed forward towards the urethra.

Diaphragm Use
Some women who use a diaphram are likely to develop a urinary tract infection. Also women whose partners use a condom with spermicidal foam also tend to have in the vagina growth of E. coli bacteria which may enter the urethra.

Frequent Intercourse: Honeymoon Cystitis
In some women, high sexual activity may traumatize the urethra, disrupting its lining and making it more susceptible to infection. This is frequently called honeymoon cystitis.

The Elderly
Older adults are at high risk for developing bladder infection (cystitis), with the incidence being as high as 33 out of 100 people.

What may place the elderly at increased risk for developing bladder infection is:

• lack of adequate fluids,
• bowel incontinence,
• decreased mobility or immobility, or
• placement in a nursing home (a stress factor).

Postmenopausal
In postmenopausal women usually vaginal tissues start to break down due to a decrease in estrogen levels; therefore, in general, the rate of urinary tract infections gradually increases with age.

Urinary Incontinence
Urinary tract infection also can be one of the risk factors for a urinary bladder problem such as incontinence - leakage of urine that interferes with some of your normal activities, often causing embarrassment or discomfort in social situations.

Incontinence, however, is not a disease, but rather a symptom of another medical condition involving the urinary system. Some causes, such as urinary tract infections, may be temporary. Others can be long-lasting, such as prostate enlargement (BPH) in men blocking the urethra or - as an effect of prostate surgery (prostatectomy).

Urinary incontinence can have a varying impact on peoples lives. In many cases it can be very distressing and embarrassing, often preventing one living a normal life. This embarrassment prevents many people seeking help. This is a pity as there are many things that can be done to help.

Failure to Completely Empty the Bladder
This failure is associated with such conditions, mainly obstructions, as:

• kidney stones,
• tumor,
• urethral strictures, or
• neurological diseases.

Urinary Tubes, Stents, or Catheters
An obstruction in the urinary tract that tends to increase the likelihood of infection can be due to:

• nephrostomy tubes (a tube inserted into the kidney to drain urine to the abdominal surface), or
• ureteric stents (a wire tube fitted in the urethra to keep the passage open), or
• urinary catheters (a small tube inserted into the bladder through the urethra to drain urine) - a usual cause of urinary tract infection due to bacteria on the catheter, especially in the elderly or those who:
  • lose bladder control, or
  • are unconscious, or
  • are critically ill (due to nervous system disorder).

Catheterization in males is more difficult and uncomfortable than in females because of the longer urethra.

Read more about urinary tubes, stents and catheters...

Diabetic Bladder Disfunction
Diabetics are at a higher risk of a urinary tract infection due to the unfavourable metabolic changes, especially the elevated blood sugar levels, which suppress their immune system.

The incidence of the urologic complications of diabetes, such as autonomic neuropathy affecting the urinary bladder, ranges from 27 percent to 85 percent.

In addition to autonomic bladder dysfunction in diabetes, there is an increased incidence of asymptomatic and symptomatic bacteria, which can progress to kidney infection and kidney damage.

This increase in bladder infection in diabetes has been attributed to numerous etiologies, such as:

• incomplete bladder emptying,
• changes in bladder cell wall components, and
• immune dysfunctions in the urothelial cells.

However, there are very few published research studies which address either the clinical aspects of bladder dysfunction in the diabetics or the basic molecular and cellular aspects of the diabetic bladder.

Neurogenic Bladder: Spinal Cord Impairment (SCI)
Neurological conditions like paraplegia or quadriplegia - a spinal cord injury, also called spinal cord impairment (SCI) - usually result in neurogenic bladder - an unstable or atomic bladder, with no muscle tone.

Men with spinal cord injuries have lost, partial or complete, control over their bladder and sphincter due to the compromised nerve receptors that are responsible for:

• contracting and relaxing the muscles of the bladder and the sphincter, and
• registering feelings of pressure or release.

Due to this condition, most paraplegics and quadriplegics are exposed to the regular use of catheters and drugs. The more traditional cap and bag, with continual drainage, is falling from favor even though it is a safer system.

However, catheters often increase the risk of urinary tract injuries and repeated bladder infections - a common problem in people with spinal cord impairment.

Exposed to repeated or long-term courses of antibiotics, in time, they also develop resistance to drugs what makes maintaining healthy urinary tract for them even more difficult.

However, contrary to a popular belief and common medical practice, men with spinal cord injuries or spinal cord impairment do not have to:

• suffer from chronic bladder infections and
• be exposed to countless rounds of vicious antibiotics.

History of Childhood Urinary Tract Infections
A history of urinary tract infections or bladder infections in childhodd also poses a risk for recurrences in adult life.

Congenital Abnormality: Vesico-Ureteric Reflux
Abnormal structure of the bladder can be something that you are born with or that develops later in life. Vesico-ureteric reflux is a congenital abnormality of the urinary tract that some children are born with, in which urine flows back into the ureters or kidney during urination.

Suppressed Immune System: Chronic Illness
Urinary tract infections occur when the immune system is supressed or compromised due to chronic illness, such a diabetes, AIDS, and cancer.

Blood Type
People with certain blood types attract bacteria which attach to cells that line the urinary tract, causing recurrent urinary tract infections.

Urinary Tract Infection: Prevention: Health Tips

Bladder infections occur when microbes, mainly bacteria, get through the urethra into the bladder. This can happen by the way you wipe after going to the bathroom, or through sex.

Bladder infections can also be caused by a blockage of urine flow, which may occur in pregnant women or in men with an enlarged prostate.

• Practice good personal hygiene by keeping the genital area clean. Less than careful hygiene, especially after developing loose stools or diarrhea is one of the most frequent causes of recurrent bladder infections.

• Urinate when you feel the need. Do not resist the urge to urinate!

• Take showers> instead of tub baths.

• Use only white unscented and, preferably, unbleached toilet paper. You may react to the dyes and chemicals in the commercially available toilet papers. Unbleached toilet paper would be even better to reduce any possible chlorine exposure and the environmental contamination that comes from the bleaching process.

• Cleanse the genital area before sexual intercourse. Wash the vulva, penis, hands and/or dildo with soap and water prior to vaginal penetration. This will reduce the risk of introducing bowel bacteria into the vagina and urethra. If condoms are used during anal contact, be sure to change condoms.

• Avoid sexual intercourse 'from behind.'

Women In Particular

If you are a woman:

• Wipe from front to back after you go to the bathroom. It helps prevent bacteria around the anus from entering the vagina or urethra. It is very easy to contaminate one's fingers when wiping oneself with toilet paper, and if those contaminated fingers come anywhere close to the opening of the urethra, there is a high likelihood of infection, especially in predisposed individuals.

• Change sexual positions. Choose the position that causes less friction on the urethra.

• Lubricate adequatly during sexual intercourse. It will decrease urethral irritation.

• Urinate after sexual intercourse. Do a "flush technique" within ten (10) minutes, if possible. If not, drink 10-12 ounces of water immediately after intercourse. It will cause you to urinate later and help flush the bacteria out.

• Avoid wet or tight clothing. Wear loose pants.

• Do not wear a wet bathing suit for a long time.

• Avoid nylon underwear and Spandex clothing. They promote moistness and irritation of the meatus (urethral opening). Wear cotton underwear instead. It is less irritating and provides more ventilation than nylon.

• Use pantyhose with cotton crotches.

• Avoid chemicals such as feminine hygiene sprays, bubble baths, strong soaps and douches. They may irritate the urethra.

Men In Particular

If you are a man:

• Practice safe sex. Use condoms to prevent infections, especially transmitted through sexual contact.

• Always wash the penis gently pulling back the foreskin when bathing or taking shower.
  
  PLEASE NOTE: An uncircumcised male has a higher chance of bladder infections only during the first year of life. This risk goes away after age one. Therefore, it is no longer true that circumcision leads to a significant decrease in the risk of bladder infections.

Uribiotic: A Broad-Spectrum Herbal Antibiotic

Over the years, at Full of Health, we have learned that urinary tract infections can be addressed naturally. With the help of antibacterial and anti-inflammatory herbs, nutrients and phytonutrients, it is possible to get through both acute and chronic infections by:

• disinfecting the urinary tract (an antimicrobial action),
• inhibiting and preventing inflammation,
• enhancing the growth of some forms of beneficial bacteria within the body such as Bifidobacteria bifidus and Lactobacillus acidophilus,
• destroying some forms of detrimental fungi such as Candida albicans and Candida krusei.

By preventing bacterial cell division and breaking down the walls and cytoplasm of bacteria (in a similar fashion to some types of pharmaceutical antibiotics), Uribiotic Formula helps to inhibit the growth (or kill) many types of detrimental pathogenic bacteria including:

• Actinomyces naeslundii
• Bacillus anthracis (on the basis of its known ability to kill other species of Bacillus)
• Bacillus alvert
• Bacillus cereus
• Bacillus subtilis
• Brucella abortus
• Campylobacter jejuni
• Chlamydia pneumoniae
• Chlamydia trachomatis
• Citrobacter freundii, a species of motile, gram-negative Citrobacter - a genus of gram-negative coliform bacteria in the Enterobacteriaceae family. Citrobacter bacteria can be present in the intestines, feces, soil, water, urine, sewage and food; they are also the source of infant meningitis and sepsis.
  Citrobacter freundii strains have inducible ampC genes encoding resistance to ampicillin and first-generation cephalosporins.
• Clostridium species (botulinum, tetani)
• Cornybacterium diphtheriae
• Enterobacter aerogenes, gram-negative aerobe, also known as Klebsiella mobilis or Klebsiella aerogenes (the latter at one time was used for several strains now known to belong to Klebsiella pneumoniae; now it is used primarily by researchers who believe that Enterobacter aerogenes should be transferred to Klebsiella)
• Enterococcus faecalis (gram-positive aerobe, former Group D streptococcus)
• Eschericia coli (E. coli, gram-negative aerobe)
• Helicobacter pylori (H. pylori)
• Haemophilus influenzae
• Klebsiella pneumoniae (gram-negative aerobe)
• Legionella pneumoniae
• Listeria monocytogenes
• Moraxella catarrhalis
• Mycobacterium smegmatis
• Mycobacterium tuberculosis
• Neisseria gonorrhoeae
• Neisseria memingitidis
• Pasteurella septica
• Pneumocystis carinii
• Propionibacterium acnes
• Proteus mirabilis (gram-negative aerobe)
• Proteus vulgaris (gram-negative aerobe)
• Pseudomonas aeruginosa (gram-negative aerobe)*
• Pseudomonas cepacia
• Salmonella enteridis
• Salmonella enteritidis
• Salmonella choleraesuis
• Salmonella paratyphi A
• Salmonella typhimurium
• Serratia marcescens (gram-negative aerobe)
• Shigella dysenteriae
• Shigella flexneri
• Shigella sonnei
• Staphylococcus aureus (gram-positive aerobe, responsible for "Golden Staph")**
• Streptococcus faecalis (now classified as Enterococcus faecalis)
• Streptococcus mutans (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
• Streptococcus pneumoniae (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
• Streptococcus pyogenes (beta-hemolytic Streptococcus), also known as Group B Streptococcus (GBS)
• Streptococcus sanguis (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
• Streptococcus viridans (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
• Streptomyces species
• Treponema pallidum
• Ureaplasma urealyticum - a species of detrimental ureaplasma bacteria, a genus of bacteria belonging to the family Mycoplasmataceae. Mycoplasma, also known as Asterococcus, is a genus of aerobic to facultatively anaerobic, gram-negative detrimental bacteria. Several species are pathogenic in humans, including Mycoplasma fermentans, Mycoplasma genitalum and Mycoplasma pneumoniae.
  U. urealyticum - the phylogenetic cluster of M. pneumoniae, is part of the normal genital flora of both men and women. It is found in about 70 percent of sexually active humans. It is believed to be sexually transmitted and transmitted from mother to infant.
  Ureaplasma urealyticum infection may cause urinary tract infections (UTIs), urinary tract/kidney stones (struvite stones), non-specific urethritis (NSU), nongonorrheal urethritis and prostatitis in men. It has also been noted as one of the infectious causes of sterile pyuria (pus in urine).
  Penicillins are ineffective as U. urealyticum does not have a cell wall, which is the drug's main target.
• Vancomycin-Resistant Enterococcus (VRE)

* PLEASE NOTE: Pseudomonas aeruginosa is a common bacterium found in soil, water, skin flora and most man-made environments. An opportunistic pathogen of immunocompromised individuals vulnerable to infections, it typically infects the pulmonary tract, urinary tract, burns, wounds, and also causes other blood infections.

P. aeruginosa is the third leading cause of hospital-acquired urinary tract infections, accounting for approximately 12 percent of all infections of this type. They are usually related to urinary tract catheterization, instrumentation or surgery.

It is a common cause of post-operative infection in radial keratotomy (RK) eye surgery patients and of "hot-tub rash" (dermatitis), caused by lack of proper periodic attention to water quality.

P. aeruginosa appears to be among the most adherent of common urinary pathogens to the bladder uroepithelium. An infection can occur via an ascending or descending route.

P. aeruginosa can also invade the bloodstream from the urinary tract. This route is the source of approximately 40 percent of P. aeruginosa infections.

P. aeruginosa can cause chronic opportunistic infections. These kinds of infections are a serious problem for medical care. Many patients, immunocompromised and the elderly in particular, often cannot be treated effectively with traditional antibiotic therapy.

As a highly relevant opportunistic pathogen, P. aeruginosa has low antibiotic susceptibility. It is naturally resistant to a large range of antibiotics and may demonstrate additional resistance after unsuccessful treatment.

Therefore, choosing an antibiotic should be guided according to laboratory sensitivities, rather than empirically. However, if antibiotics are started empirically - with some exceptions, given by injection only - then cultures should be obtained and, after having the culture results available, the choice of an antibiotic used should be carefully reviewed.

April 17, 2009: Thanks, Andrew, for your advice and support with my Pseudomonas [aeruginosa] bladder infection with your amazing product Uribiotic which stopped the infection and kept it away. I've suffered from UTIs for 18 years since my spinal cord injury and now I'm infection free. JASON C. Great Britain

** PLEASE NOTE: In case of Staphylococcus aureus infections, Uribiotic Formula can be a part of a combined antibiotic therapy as it may enhance the effectiveness of pharmaceutical antibiotics for the UTI treatment.

Uribiotic Formula: An Immune Booster

An immune-boosting Uribiotic Formula helps to increase the natural safeguards - bodily defense systems that protect the urinary tract against pathogenic, infection-causing bacteria, such as:

• the flow of urine which functions as an antiseptic, helping to wash potentially harmful bacteria out of the body during normal urination. (Urine is normally sterile, that is, free of bacteria, viruses, and fungi!)
• the ureters (muscular ducts that propel urine from the kidneys to the urinary bladder) and the bladder
• the immune defenses and antibacterial substances in the mucous lining of the bladder
• the bladder lining cells that, literally, sacrifice themselves and self-destruct to fight off detrimental bacteria (a process called apoptosis). In so doing, they fall away from the lining, carrying the bacteria with them. This process, suggested by some interesting research, eliminates about 90% of the E. coli
• the vagina which is colonized - in normal fertile women - by lactobacilli, beneficial micro-organisms that maintain a highly acidic environment (low pH). Lactobacilli also produce hydrogen peroxide, which helps eliminate bacteria and reduces the ability of E. coli to adhere to vaginal cells
• the so-called human beta-defensin-1 (HBD-1) which fights E. coli within the female urinary and reproductive tracts -.a possible natural antibiotic identified by some researchers
• the antibacterial actions of some secretions of the prostate gland probably for why men are less likely than women to develop urinary tract infection.

Uribiotic Formula: Health Benefits Summary

It is so embarrassing having consult your doctor for the same reason (another infection!) and need to take another round of antibiotics.

The truth is, however, that urinatry tract infections CAN be successully remedied and prevented without multiple rounds of prescription medications (antibiotics).

Health benefits of our proprietary Uribiotic Formula - a synergistic blend of 59 nutrients, phytonutrients (plant nutrients) and herbs thoroughly researched and put to the test - include:

• anti-inflammatory,
• antibacterial,
• antifungal,
• antiviral,
• antiparasitic,
• antioxidant,
• diuretic,
• anti-edematous (decreasing edema and swelling), and
• antitumor.

Thousands of people around the world have proven the efficacy of this approach. And what is most important, there has not been a single reported harm done by taking the Uribiotic Formula.

Uribiotic® The Genuine Mierzejewski Formula™ Advanced Urinary Tract Support * 63 Vegetarian Capsules 59 Phytonutrients and Nutrients SUPPLEMENT FACTS: Amount Per Serving (3 Capsules)
1. Vitamin A (All Trans Retinyl Palmitate)	1,500 IU
2. Vitamin C (Calcium Ascorbate)	60 mg
3. Vitamin E (d-Alpha-Tocopherol Succinate)	25 IU
4. Riboflavin (Vitamin B-2)	5 mg
5. Vitamin B-6 (as Pyridoxine HCl)	5 mg
6. Biotin	300 mcg
7. Magnesium (Taurinate)	150 mg
8. Zinc (Monomethionine)	25 mg
9. Selenium (Selenomethionine)	25 mcg
10-59. PROPRIETARY BLEND:
Grape Seed Extract (std. to 90% Oligomeric Proanthocyanidins), Saw Palmetto Berry Powder Extract (Serenoa repens) (std. to 25% Fatty Acids), Uva Ursi Extract (Arctostaphylos uva-ursi) (std. to 20% Arbutin) (leaf), Oregano Leaf (Origanum vulgare) (std. to 10% Thymol), Echinacea STD [Echinacea angustifolia (root) and Echinacea purpurea (aerial parts)], Berberine (Berberis aristata) (Barberry Root Extract, 4:1), Propolis 2:1, Goldenseal Root (std. to 9% Alkaloids, incl. 5% Hydrastine), Grapefruit Seed Extract, Olive Leaf Extract (Olea europaea), Buchu Leaf Extract (Barosma betulina), Corn Silk (Zea mays), Meadowsweet (Spirea Ulmaria), Stinging Nettle Leaf Extract (Urtica dioica) (std. to 1% silica), Couch Grass (Agropyron repens) (root), Cranberry Powder (fruit) (Vaccinium macrocarpon) (90% Cranberry solids), Garlic (Allium sativum) (bulb), Gotu Kola (Centella asiatica) (leaf), Lactoferrin, Purple Mangosteen Extract (Garcinia mangostana) (std. to 10% Mangostin) (pericarp/rind), Onion Extract (Allium cepa) (bulb), Horsetail Grass STD (Equisetum arvense) (stem), Pau D'Arco (Tabebuia impetiginosa) (bark), Asparagus Shoot (Asparagus officinalis), Astragalus Root Extract (Astragalus membranaceus) (std. to 0.3% Astragalosides), Bay Laurel Leaf Powder (Laurus nobilis), Beta-Sitosterol, Eastern Black Walnut Hull (Juglans nigra), Cloves (Syzygium aromaticum) (fruit), N-Acetyl-L-Cysteine, Pomegranate Extract (std. to 40% Ellagic Acid) (whole fruit), Troxerutin Complex (std. to 85% Troxerutin), Cayenne Fruit (Capsicum annuum), Cinnamon Bark Extract, Great Yellow Gentian (Gentiana lutea) (root), Hesperidin (peel), Rosemary Leaf Extract (Rosmarinus officinalis) (std. to 6% Carnosic Acid), Eleutherococcus senticosus (std to 0.8% Eleutherosides) (root), Horse-Chestnut Extract (Aesculus hippocastanum) (std. to 20% Escin) (fruit), Silymarin Extract STD (from Milk Thistle seed), Bromelain, Chlorophyll (as Sodium Copper Chlorophyllin), Papain, Vinpocetine, Trans-resveratrol (from Grape Vine Shoot Extract), Vanadium (as Vanadyl Sulfate), BioPerine® Black Pepper Extract (Piper nigrum) (fruit), Lycopene Extract, Boron (from Boron Citrate).	1,144 mg
Other ingredients: Hydroxypropylmethylcellulose (vegetable capsule), microcrystalline cellulose, vegetable stearate and silica.
This product is manufactured in a NSF GMP registered facility in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.	QUALITY & SAFETY ASSURANCE
Take 3 capsules 3 times daily in between meals (beginning after breakfast), each time with 4 ounces (˝ cup) of purified lukewarm water, or as recommended by a qualified healthcare professional.	DIRECTIONS
If you are under a physician’s care or taking medication, or if you are pregnant or nursing, consult your healthcare practitioner before using this product.	CAUTION
Quality and purity guaranteed. This product does not contain MSG, wheat, gluten, soy protein, fish, shellfish, milk/dairy, corn, egg, nuts, sugar, salt, starch, artificial coloring, preservatives, or flavoring.	PREMIUM PURITY
FULL OF HEALTH, INC. Since 1996 Uribiotic® Formula: Advanced Urinary Tract Support * * This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Full of Health and Uribiotic are registered trademarks of Full of Health, Inc. BioPerine® is a registered trademark of Sabinsa Corporation.

Healing Properties

Uribiotic Formula can cause the almost instant disappearance of the painful burning sensation when urinating, the need for frequent urination, the inability to empty the bladder completely even though you have the urge. Uribiotic Formula can help you eliminate: the harmful bacteria from the inside of the urinary tract and without disrupting the normal body functions. Uribiotic Formula can help you prevent and remedy: both acute and repeated (chronic) urinary tract infections, and the need and dependence on antibiotics.

Recommended Intake

Upon the first signs of urinary tract infection, begin taking 3 capsules of the Uribiotic Formula 3 times daily (morning - beginning after breakfast, noon, afternoon) 20 minutes apart from having food, each time with ˝ glass of purified lukewarm water.

Also do your best and try to sip lots of water throughout the day.

PLEASE NOTE: If necessary, Uribiotic Formula can be a part of a combined antibiotic therapy as it may enhance the effectiveness of pharmaceutical antibiotics for the treatment of urinary tract infections (UTIs), especially in case of Staphylococcus aureus infections.

First Signs of Relief Within 24-48 Hours

You should experience the first signs of relief within 24-48 hours after you begin taking the Uribiotic Formula. The symptoms should be cleared within 7 days, provided you will keep taking the Uribiotic Formula consistently without skipping doses.

However, the results may vary from person to person depending on the diagnosis, degree of UTI, age, sex and other existing health conditions.

Our Clients Write to Us:

April 29, 2011 Hello, again, Full of Health Team! I just got on to your website to order more URIBIOTIC... I am the "Katie B." from Denver, Colorado! My testimonial has been on your home page for over 2 years now. I have been living in China for the past year and I just recently got a bladder infection for the first time in over 2 years! You have no idea how comforting it has been to have the assurance of having your product in my medicine cabinet while living in such a foreign land with foreign doctors and hospitals. I was quite scared when I got the bladder infection a couple of days ago, because I thought, "what if it just doesn't work this time and I have to go to a hospital in China?!" But, have no fear… URIBIOTIC worked for me AGAIN! THANK YOU FOR YOUR AMAZING PRODUCT!!!! I sing your praises every time I have sex -:) Thank you and have a great weekend! Katie

June 19, 2009 Thanks, Andrew! I got a severe bladder infection and also discovered I had an enlarged prostate. I was in bad pain when I often had to go to restroom. One night I was going every 30 minutes. They put me on sulfa antibiotics and also wanted me to take Flowmax which I told them I would not take. I don't like taking antibiotics if I can help it. They also did a CAT scan. I took the antibiotics for a few days but they did not help that much. Until I got my I order of Uribiotic in. I started taking it and, after a few days, noticed feeling a little better each day. I started going to the bathroom about twice a night. Then just once a night and now I never wake to go to the bathroom. My measured urine outflow in the morning became normal and with no pain. I was also taking DP Extract for my enlarged prostate for about six weeks. Then I went to a specialist and he checked me and said that my prostate was normal. He said I don't need to come back. Now everything is back to normal. I still take both Uribiotic and DP Extract. I am very thankful for your help and advice, Andrew. Aaron Hiller Texas

July 14, 2007 Problem solved! The infection is GONE! I just thought you might want to know this in case you get any customers notifying you that URIBIOTIC doesn't seem to be working. I love your product and continue to rave and refer anyone I talk to about UTIs to your website. THANK YOU FOR CREATING THIS PRODUCT!!! Katie B. Denver, Colorado

No Side Effects

Formulated with care by a master formulator and manufactured according to the highest standards *, this unique synergistic combination can help you deal with your bladder and/or even kidney infection:

• safely,
• effectively, and
• with no side effects.

* QUALITY & SAFETY ASSURANCE: Uribiotic Formula is manufactured in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.

Cautions and Contraindications

Sexual System:
Uribiotic Formula is not recommended to be taken during pregnancy as it can cause contractions of the uterus due to presence of Goldenseal, Vinpocetine and hydroquinone (via arbutin present in Uva Ursi/Bearberry).

Cardiovascular System:
Uribiotic Formula should be consumed with caution by patients with severe hypertension (high blood pressure) due to the presence of Nettle root as it may further raise blood pressure in some people. However, Olive Leaf Extract, Rutin and Siberian Ginseng (Eleutherococcus senticosus) present in the Uribiotic Formula may actually help lower blood pressure in hypertension patients.

Pharmaceutical Drugs:
Uribiotic Formula should be consumed with caution by patients on a high dose of warfarin (blood thinner) due to the presence of garlic which may potentiate the anticoagulant effects of warfarin. (Reference: Fugh-Berman, A. Herb-drug interactions. Lancet. 355(9198):134-138, 2000).

PLEASE NOTE: When acute nephritis (kidney infection) is present - accompanied by high fever along with sudden retention of urine (a painful urge to pass urine but the inability to do so) - have your condition assessed immediately by your physician.

Simple and Astonishingly Effective

Our proprietary Uribiotic Formula is so simple and astonishingly effective that it continues to amaze even the most skeptical people.

For this reason, we have decided to go worldwide and share our experience with the public on the Internet to help people around the world to remedy bladder and/or even kidney infection.

So far, we have introduced our proprietary Uribiotic Formula to our clients and customers in 32 countries: the United States, Australia, the United Kingdom, South Africa, New Zealand, Germany, Belgium, Mexico, Italy, Singapore, France, Russia, Croatia, Poland, Portugal, Denmark, United Arab Emirates, Hong Kong, St. Lucia (West Indies), Norway, Saudi Arabia, Turkey, Slovenia, Greece, Qatar, Jordan, Israel, the Netherlands, Luxembourg, Sri Lanka, India, and Spain.

With no doubt this superb supplement can be of great benefit to you. You have nothing to lose - and lots to gain. And if necessary, it can be a part of a combined antibiotic therapy as Uribiotic Formula may even enhance the effectiveness of standard pharmaceutical antibiotics for the treatment of urinary tract infections (UTIs), especially in case of Staphylococcus aureus infections.

Therapeutic and Preventive Intake: Directions

With possible variations from person to person, the suggested intake of the Uribiotic Formula - depending on the diagnosis, degree of UTI, sex, age and other existing health conditions - can be described as follows: I. Acute UTI: In case of first signs of discomfort (slight burning sensation when urinating, frequent urination and/or inability to empty bladder completely) you need to take: 3 capsules 3 times daily; therefore, for full benefits, at least 1 bottle of the Uribiotic Formula is needed (an initial 7-day therapeutic intake). In case persistent signs of UTI (painful burning sensation when urinating, frequent urination at night and/or inability to empty bladder completely) you need to take: 3 capsules 3 times daily; therefore, for full benefits, 2 bottles of the Uribiotic Formula are needed (an extended 14-day therapeutic and prophylactic intake). II. Chronic/Repeated UTI: In case of recurrent, repeated UTIs (all the above symptoms along with the need and dependence on antibiotics) it is necessary to take: 3 capsules 3 times daily; therefore, for full benefits, 3 bottles of the Uribiotic Formula are needed (an intensive 21-day therapeutic and prophylactic intake) DIRECTIONS: Take the capsules throughout the day in between meals (on an empty stomach), preferably before 6 pm, each time with ˝ glass of purified lukewarm water. PLEASE NOTE: After all symptoms have disappeared, in order to restore the urinary tract’s normal pH and, thus, prevent recurring UTIs, taking 1 capsule of the Uribiotic Formula 3 times daily for at least 7 consecutive days is highly recommended. ADDITIONAL RECOMMENDATION: In order to fully exert the therapeutic, protective and preventive (prophylactic) effects of the Uribiotic Formula, it might be taken along with probiotics in order to suport friendly urogenital flora, such as Probiotic LGG Plus: Friendly Urogenital Flora Support. CAUTIONS: Uribiotic Formula is not recommended for pregnant women. Also patients with severehypertension (high blood pressure) should take it with caution. However, Olive Leaf Extract, Rutin and Siberian Ginseng (Eleutherococcus senticosus) present in the Uribiotic Formula may actually help lower blood pressure in hypertension patients). It should also be taken with caution by patients on aaa high dose of warfarin (blood thinner) due to the presence of garlic which may potentiate the anticoagulant effects of warfarin. (Reference: Fugh-Berman, A. Herb-drug interactions. Lancet. 355(9198):134-138, 2000). PLEASE NOTE: When acute nephritis (kidney infection) is present - accompanied by high fever along with sudden retention of urine (a painful urge to pass urine but the inability to do so) - have your condition assessed immediately by your physician. Do Not Stop! Although symptoms-free, please DO NOT stop taking the Uribiotic Formula and continue to use it until the bottle is empty (up to 7 days). If you are prone to repeated/chronic urinary tract infections keep an extra bottle of the Uribiotic Formula on hand and use it immediately at the first signs of infection for the minimum of 3 consecutive days. In time, you will notice that the frequency of your urinary tract infections begins to seize, making the further use of the Uribiotic Formula - with some possible exceptions - unnecessary and/or occasional only. Male Adults with BPH: Although we have found the Uribiotic Formula effective in both women and men, the latter - besides bladder infections - quite offten suffer from undiagnosed prostate infection (prostatitis) and/or benign prostatic hyperplasia (BPH), a non-cancerous swelling of the prostate gland. If this is a case, for full benefits we recommend taking the Uribiotic Formula along with another herbal supplement: European DP Extract: Enlarged Prostate (BPH) Remedy

Secure Online Orders

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 Uribiotic Orders: United States and Worldwide 
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Phone/Fax Orders

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If you do not feel comfortable placing your order online, please call us:

• 1. 705. 876. 9357 (US/Can), Mon-Fri: 10:00 am - 3:00 pm EST (Weekends and Holidays Excluded).

Leave your name, phone number, and the best time to call you.

You can also fax your order:

• 1. 705. 876. 8592 (US/Can).

Please include your full name, shipping address, phone number, and your preferred method of payment.

Bladder Infections & Spinal Cord Injuries

Neurological conditions like paraplegia and quadriplegia - a spinal cord injury, also called spinal cord impairment (SCI) - usually result in a neurogenic bladder, that is an unstable or atonic bladder (with no muscle tone).

People with spinal cord injuries have lost, partial or complete, control over their bladder and sphincter due to the compromised nerve receptors that are responsible for:

• contracting and relaxing the muscles of the bladder and the sphincter, and
• registering feelings of pressure or release.

Due to this condition, most paraplegics and quadriplegics are exposed to the regular use of catheters and drugs. (Even though it is a safer system, the more traditional cap and bag with continual drainage is falling from favor).

However, catheters often increase the risk of the urinary tract injuries and repeated bladder infections - a common problem in people with spinal cord impairment.

Exposed to repeated or long-term courses of antibiotics, in time, they also develop resistance to drugs what makes maintaining healthy urinary tract for them even more difficult.

Contrary to a popular belief and common medical practice, people with spinal cord injuries or spinal cord impairment do NOT have to:

• suffer from chronic bladder-kidney infections and
• be exposed to vicious antibiotics.

It is our clinical experience that paraplegics and quadriplegics, expecially those who use catheters, can successfully remedy, and most importantly, prevent bladder infections with the help of our proprietary UTI Uribiotic Formula.

Therefore, you, or someone you know or hold dear who suffers from spinal cord injury should give this herbal antibiotic serious consideration.

Our Clients with SCI Write to Us: Testimonials

June 29, 2011: I have been quadriplegic for 15 years. About seven years ago, I started to suffer recurrent urinary tract infections to the point where most of the bacteria had become multiresistant. My urologist pointed out to me that kidney failure is the biggest killer of people with spinal cord injuries as a result of repeated urinary tract infections which became untreatable as a result of repetitive use of antibiotics. About two years ago I developed an infection, the bacteria being pseudomonas. Antibiotics did not work and the decision was made to not use any more, live with it and hope it didn't get into my bloodstream. I couldn't accept this, so I researched the Internet once again until I finally found out about oil of oregano and Uribiotic. I ordered some, showed my GP who confirmed that there was nothing in it that could possibly cause any harm and to give it a go, which I did. Within a few weeks the urinary tract infection cleared up. I have barely had any symptoms since, and when I do I just use the Uribiotic for a couple of days and symptoms clear up. No side effects and no worries about the tablets not working. I am a skeptic and honestly didn't think this would work when I tried it, but it does. If I didn't find out about it, I hate to think where I would be now. I just wish I knew about it sooner. Janine N. Perth, Western Australia

April 17, 2009: Thanks, Andrew, for your advice and support with my Pseudomonas [aeruginosa] bladder infection with your amazing product Uribiotic which stopped the infection and kept it away. I've suffered from UTIs for 18 years since my spinal cord injury and now I'm infection free. JASON C. Great Britain

December 14, 2007: As a paraplegic for almost 14 years, I was almost constantly on antibiotics due to chronic bladder infection. However, being afraid of possible side effects, for many years I was reluctant to consider any natural alternatives. I was afraid of getting diarrhea or constipation. These are the worst - a real disaster! But after successful experience with D-Mannose, I started looking for other natural means to solve my problem. And I was pleasantly surprised by lack of any adverse reactions to URIBIOTIC, which I introduced to my system very cautiously. Two weeks later, my urine culture showed NO E. coli. Burning went away in a few days. I'm pleased to report such great results. Barret D. Minnesota

If Your Infection Persists

On rare occasions the Uribiotic Formula alone does not seem to be enough, especially when the infection has already spread into the entire urinary tract, the following remedies should also be given serious consideration:

• D-Mannose Powder PLUS
• Oregano Oil
• Probiotic LGG Plus: Friendly Urogenital Flora Support.

ATTENTION: Male Adults with BPH

Although we have found the Uribiotic Formula effective in both females and males, men - besides bladder infections - quite offten suffer from undiagnosed prostate infection (prostatitis) and/or benign prostatic hyperplasia (BPH), a non-cancerous swelling of the prostate gland.

If this is a case, for full benefits we recommend taking the Uribiotic Formula along with another herbal supplement, namely: European DP Extract: Enlarged Prostate (BPH) Remedy.

Advanced Urinary Tract Support: Our Program

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	UTI Uribiotic Formula: Bladder Infection Herbal Remedy
	D-Mannose Powder PLUS: UTI Enhanced Natural Remedy
	Oregano Oil: Powerful Natural Antimicrobial
	Probiotic LGG Plus: Friendly Urogenital Flora Support
	The Low-Grain, Low-Sugar Delight: UTI Diet & Cookbook
	FREE e-Pamphlet: Say NO! to Urinary Bladder Infection

NEED HELP OR ADVICE?
Contact us by or by phone: 1. 705. 876. 9357 (US/Can)
Mon-Fri: 10:00 am-3:00 pm EST (Weekends & Holidays Excluded)

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© 2003-2012 Remedy-Bladder-Infection.com. Stop Urinary Bladder Infection with UTI Uribiotic Unisex Herbal Formula. Natural UTI Cures, Treatments & Prevention. Alternative, herbal and nutritional, treatments for cystitis, and urethritis. Remedy and prevent urinary tract infection (UTI) without antibiotics and other medications. The information provided herein on bladder infection is a general overview on this topic and may not apply to everyone, therefore, it should not be used for diagnosis or treatment of any medical condition. While reasonable effort has been made to ensure the accuracy of the information on bladder infection, Full of Health Inc. assumes no responsibility for errors or omissions, or for damages resulting from use of the bladder infection information herein.
URIBIOTIC and FULL OF HEALTH are registered trademarks of Full of Health, Inc.

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About Us: Full of Health, Inc.

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