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Urinary Bladder Infection
Uropathogenic E. Coli Bacteria
The Most Common Cause of UTI
A picture of E.coli bacteria. An undated file photo from the USDA
In most cases, about 80 percent, urinary tract infection in adults is caused by a variety of pathogens (infectious bacteria) normally present in the intestines, especially in the rectum (colon).
Nearly all infections of the lower urinary tract are caused by a few strains of E. coli bacteria - uropathogenic Escherichia coli (UPEC).
Various harmless strains of E. coli are normally present in the body - but they do not belong in the urinary tract. These bacteria have multiple little hairs called cilia that function like little feet that allow them to climb from the skin around the vagina, up the urinary tube, into the bladder.
If E. coli get into the bladder or the urethra (tube that carries urine from the bladder), the body has ways of fighting them off - including the obvious methods of simply flushing them out with the urine.
These bacteria, however, have evolved ways of anchoring themselves to the cells of the urinary tract.
The invading E. coli take advantage of receptors naturally found on the cells of the mucosal lining of the urinary tract. These receptors are like molecular "docking bays" for substances which the cells need for their normal growth and development.
Like pirates in an old movie, E. coli use "grappling hooks", called type I pili, to first hook on to these
receptors, and then to invade the cell. These pathogenic grappling hooks are composed of long, fibrous chains of a molecular "glue" called adhesin.
Once inside the cell, E. coli can live and reproduce in safety, shielded from many of the body's defensive immune responses.
In fact, these immune responses are so sophisticated that when the body detects that cells have been infected and activates the cell suicide program to destroy the bacteria, E. coli can actually flee the dying host
cell before it is flushed out - and look for new cells to invade!
Repeated Bladder Infections: Possible Factors
For many women - especially those over the age of 55 years or between the ages of 25 and 29 - repeated bladder infections can be a painful and frustrating battle.
Women who have had three or more (3+) infections a year are likely to continue having them. In other words, they can get another infection within 18 months of the last one, or even more requently.
Possible multiple factors behind recurrent urinary tract infections include:
the ability of E. coli bacteria to attach to cells lining the urinary tract;
chemical irritation due to commercial toiletries, such as bath additives and washing powders;
the separate infections, stemming from a strain or type of bacteria different from the infection before (even when several urinary tract infections in a row are due to E. coli, slight differences in the bacteria indicate distinct infections), and
the inadequacy of the current standard drug (antibiotic) treatments for urinary bladder infections.
Some women, however, have recurrent symptoms suggestive of urinary tract infection - but without infection being present. Although this condition is not serious, it can be troublesome.
Because of the chance of kidney infection (pyelonephritis), repeated or chronic urinary tract infections should be always treated thoroughly to ensure that the urinary tract is free of bacteria.
Survival Rate of E. Coli Bacteria
E. coli infections return in as many as 30 percent of women apparently "cured" by antibiotics!
The bacteria are able to survive antibiotic treatment by reverting to an inactive state. Within several days of drug treatment, the number of bacteria reproducing drop to zero. But - not all the E. coli bacteria are killed!
After an antibiotic treatment, uropathogenic E. coli may be still present in a dormant state and linger in the urinary tract:
about 3 percent after ciprofloxacin hydrochloride (Cipro) treatment and
about 7 percent after trimethoprim-sulfamethoxazole, a popular two-drug (Bactrim/Septra) treatment.
Even after a month of antibiotic exposure, about 10 million of the original 1 billion bacteria may remain in the urinary tract.
Antibiotic treatment does NOT successfully kill all the bacteria participating in the infection and may, in fact, encourage many of the bacteria to persist in a resting state.
Therefore, current standard drug treatments for bladder infections are not adequate and this phenomenon may account for many of the repeat urinary tract infections.
New Antibiotic-Resistant Strain of E. Coli
A newly identified, antibiotic-resistant strain of a common E. coli bacterium is contributing to an increase in relatively hard-to-treat bladder infections in women.
The analyzed strain, resistant to trimethoprim-sulfamethoxazole, a popular two-drug antibacterial combination (Bactrim/Septra), shows a pattern of resistance to multiple antibiotics and has genetic characteristics called "virulence factors" that increase its ability to infect the urinary tract.
Not much is known about how new strains of bacteria that infect the urinary tract arise and spread. It could be that this organism has been around forever and has now acquired resistance to several antibiotics. It could have been
introduced, perhaps, through contaminated food.
D-Mannose: Non-Prescription Alternative to Antibiotics
D-mannose, a simple sugar and close cousin of glucose, can cure more than 90 percent of all E. coli bladder infections within 1 to 2 days.
Even more remarkably, D-mannose accomplishes this feat without killing a single bacterium! (Exactly how does this it will be explained later).
And because it gets rid of these bladder infection-causing bacteria without committing "bactericide," people who use it suffer none of the unwanted side effects of antibiotics:
no gastrointestinal (GI) problems,
no yeast infections, and
no resistant bacteria.
In fact, D-mannose has no adverse side effects of any kind.
It Tastes Good!
As a bonus, D-mannose actually tastes good. Where a "spoonful of sugar" helped the medicine go down in Mary Poppin's day, with D-mannose, a spoonful of sugar is the medicine.
It Is Effective and Safe!
Because it is so effective and so benign, women (even pregnant women) who are susceptible to recurrent bladder infections, can safely take D-mannose as a preventive measure to head off future E. coli attacks.
It Is Suitable for Children D-mannose is also ideally suited for children with bladder infections. Because it tastes so good (it is a sugar, after all!), children actually enjoy taking it.
It Is Just As Effective As Antibiotics
Although D-mannose is still virtually unknown to many practitioners of conventional medicine, many research reports have demonstrated its mode of action and effectiveness against E. coli, the microorganism that
causes most bladder infections.
Moreover, several years of clinical experience have shown that it is just about as effective at curing bladder infections caused by E. coli as antibiotic drugs.
It Has No Known Drawbacks
At first glance, D-mannose may sound too good to be true: a "medicine" that's highly effective, perfectly safe, pleasant to use and available without a doctor's prescription. Yet, it is true!
Unlike virtually any conventional medication, and many natural or alternative treatments as well, D-mannose has no known drawbacks.
D-Mannose Vs. Antibiotics
When faced with a potentially pathogenic germ like E.coli, conventional, pharmaceutically based medicine typically confronts the problem by throwing the most potent poisons it can find at the bugs - antibiotics.
While there is nothing essentially wrong with killing disease-causing bacteria, this approach does have some very serious drawbacks. Happily, "bacteria-cide" is not the only possible avenue of attack.
Another, more natural way to eliminate E. coli infections from the urinary tract is to beat them at their own game. If they are going to cause trouble, bacteria usually have to find a way to adhere (stick) to the body tissue they are infecting.
In bladder infection, E. coli attach to cells lining the bladder and urinary tract using filmy, hair-like
projections called fimbria on their cell walls.
At the tip of each fimbrium is a glycoprotein (a combination carbohydrate and protein) called a lectin that is programmed to bind to the first molecule of the sugar mannose that it encounters.
It turns out that molecules of mannose (produced inside urinary tract lining cells) naturally dot the surfaces of these cells. Here they act as "receptors," inviting the fimbria of E. coli to attach, and allowing
them to bind to the tissue in a tight, Velcro-like grip.
If not for this attachment to the cell's mannose, any E. coli that had successfully ventured up the urethral river would be unable to stick to the slippery surface and would be washed right back out on the next tide of urination.
How Does D-Mannose Work?
Now imagine what would happen to E. coli in the urinary tract if those sweet little mannose molecules they crave were present not just on the surface of the epithelial cells but surrounding them in the urine as well.
The E. coli could not turn around without bumping into D-mannose
"just floating around" in the urine. Unable to resist the tasty bait
they suddenly find themselves swimming in, they would latch onto the
nearest mannose molecules, and happily sail off into the porcelain sunset.
Those few E. coli left clinging to mannose molecules on cells then
become easy prey for white blood cells and other agents of the immune system.
In addition to its natural occurrence in the cells lining the
epithelial tract, the sugar D-mannose is also found in
relatively large quantities in fruit such as peaches, apples, oranges,
and certain berries, like cranberries and blueberries.
Extracted in the form of D-mannose, a white crystal sugar
similar to glucose, it can be easily dissolved in a liquid and
swallowed. (Mannose can also be synthesized from other simple
sugars.)
When someone with bladder infection consumes a dose of D-mannose, the
sugar is absorbed in the upper GI tract, but at a much slower rate than
most other sugars. (For example, glucose is absorbed more than eight
times faster.)
Moreover, unlike other sugars, D-mannose is not readily converted to glycogen (and stored) in the liver, but instead passes directly into the bloodstream largely unchanged what makes it suitable for diabetics.
As the D-mannose-laden blood passes through the kidneys, a considerable proportion of the sugar is extracted and added to the urine.
The D-mannose-sweetened urine flows from the kidneys through the ureters to the bladder and on to the urethra, literally sugar-coating any free-floating E. coli it might encounter, so they cannot stick to cells any more.
It also unsticks most of the E. coli already "velcro-ed" to the inner surface of the bladder and urinary tract, ultimately flushing them all down the drain.
D-Mannose: First Line of E. Coli Treatment
First, the "molecular mechanism" of the action of D-mannose on E. coli is scientifically proven. There is no argument at all about this among researchers who have studied it.
Second, literally tens of thousands of women working with natural medicine doctors have successfully applied this science to their own bladder infections.
Considerable circumstantial evidence, combined with common sense and several of clinical experience, makes a compelling case for the therapeutic value of D-mannose.
Laboratory Studies
In one laboratory study, for example, rats' urinary tracts were inoculated with E. coli. Within one day, those rats also given D-mannose were found to have significantly lower levels of bacteria in their urine.
In another study, administering a mannose-like substance (niethyl a-D-mannopyranoside) to E. coli-infected mice led to a 90 percent reduction in bacterial attachment to the urinary tract.
Research in humans shows that ingesting D-mannose significantly elevates blood mannose levels, a prerequisite if urinary levels are to rise.
Epidemiological Evidence
Perhaps the best available evidence, though, comes from the experience of people who have used it. Natural medicine-oriented physicians have been recommending D-mannose to people with bladder infection since the mid-1980s with great success.
In one case, a 5-year-old girl had almost continuous bladder infections for her entire life that had failed to respond to every antibiotic therapy her physicians tried (72 doctors in all!).
At the end of their rope, her doctors were now considering a kidney transplant, since her kidneys were starting to fail due to years of chronic infection.
Since urine culture showed her bladder infection was due to E. coli, she was started on D-mannose (1 tsp in a glass of water every 2-3 hours). Within 48 hours, her infection had vanished, and her kidneys were saved!
"Honeymoon Cystitis" D-mannose can also be very effective in cases of "honeymoon
cystitis." It is not uncommon for women to avoid sex because they get a
bladder infection nearly "every time" they have intercourse.
If a urine culture shows the presence of E. coli, taking D-mannose, 1 teaspoon 1 hour prior to intercourse, will mostly likely completely eliminate further infections.
Recurrent Bladder Infections
Physicians experienced with D-mannose report that women prone to
very frequent recurrent bladder infections that are not necessarily
related to sexual intercourse can also often benefit from taking
D-mannose preventively. To save expense, some women have been
able to "taper down" their dosage and dose frequency.
Single Bladder Infections
By far the most frequent success with D-mannose has been achieved by the thousands of women who have suffered single (non-recurrent) episodes of E. coli bladder infection. In 90 percent of such cases, 1 teaspoon of D-mannose every 2 to 3 hours usually clears the infection in 1 to 3 days.
Other Ingredients: Natural mixed berry flavor, xylitol, citric acid, silicon dioxide and stevia extract.
Contains no added starch, salt, wheat, gluten, corn, coloring, dairy products, or preservatives.
Keep container tightly closed in a cool, dry and dark place. Keep out of reach of children.
Recommended Intake
Directions: Mix 1 level teastoon (4.7 grams) in 4 to 6-ounces of purified, cold water.
For relief from a urinary tract infection, repeat four to six (4-6) times per day.
For prevention of a urinary tract infection, drink once or twice a day.
Description:D-Mannose is a naturally occuring simple
sugar, closely related to glucose. Clinical studies have demonstrated
its ability to prevent E. Coli bacteria from adhering to the
inner walls of the bladder, potentially reducing the incidence and
severity of urinary tract infections. D-Mannose Powder PLUS
combines d-Mannose with Cranberry extract to enhance its
effectiveness.
These statements have not been evaluated by the Food and Drug Administration (FDA). This product is not intended to diagnose, treat, cure or prevent any disease.
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If Your Infection Persists
Although a bladder infection caused by E. coli responds to D-mannose with a significant symptom reduction within 24 hours, the treatment should be continued for 2 to 3 days after the last symptom is gone, just to "make sure."
However, if a bladder infection treated with D-mannose does not show significant improvement within 24 hours (about 10 percent of cases), it is likely that the causative organism is not E. coli.
In this case, as the untreated infection may spread into the upper urinary tract, namely, the kidneys, causing serious problems, the other natural remedies should be considere, namely:
Over the years, at Full of Health, we have learned that urinary tract infections can be addressed naturally. With the help of antibacterial and anti-inflammatory herbs, nutrients and phytonutrients, it is possible to get through both acute and chronic infections by:
disinfecting the urinary tract (an antimicrobial action)
inhibiting and preventing inflammation
enhancing the growth of some forms of beneficial bacteria within the body such as Bifidobacteria bifidus and Lactobacillus acidophilus
destroying some forms of detrimental fungi such as Candida albicans and Candida krusei.
By preventing bacterial cell division and breaking down the walls and cytoplasm of bacteria (in a similar fashion to some types of pharmaceutical antibiotics), Uribiotic Formula helps to inhibit the growth (or kill) many types of detrimental pathogenic bacteria including:
Actinomyces naeslundii
Bacillus anthracis (on the basis of its known ability to kill other species of Bacillus)
Bacillus alvert
Bacillus cereus
Bacillus subtilis
Brucella abortus
Campylobacter jejuni
Chlamydia pneumoniae
Chlamydia trachomatis
Citrobacter freundii, a species of motile, gram-negative Citrobacter - a genus of gram-negative coliform bacteria in the Enterobacteriaceae family. Citrobacter bacteria can be present in the intestines, feces, soil, water, urine, sewage and food; they are also the source of infant meningitis and sepsis. Citrobacter freundii strains have inducible ampC genes encoding resistance to ampicillin and first-generation cephalosporins.
Clostridium species (botulinum, tetani)
Cornybacterium diphtheriae
Enterobacter aerogenes, gram-negative aerobe, also known as Klebsiella mobilis or Klebsiella aerogenes (the latter at one time was used for several strains now known to belong to Klebsiella pneumoniae; now it is used primarily by researchers who believe that Enterobacter aerogenes should be transferred to Klebsiella)
Enterococcus faecalis (gram-positive aerobe, former Group D streptococcus)
Eschericia coli (E. coli, gram-negative aerobe)
Helicobacter pylori (H. pylori)
Haemophilus influenzae
Klebsiella pneumoniae (gram-negative aerobe)
Legionella pneumoniae
Listeria monocytogenes
Moraxella catarrhalis
Mycobacterium smegmatis
Mycobacterium tuberculosis
Neisseria gonorrhoeae
Neisseria memingitidis
Pasteurella septica
Pneumocystis carinii
Propionibacterium acnes
Proteus mirabilis (gram-negative aerobe)
Proteus vulgaris (gram-negative aerobe)
Pseudomonas aeruginosa (gram-negative aerobe)*
Pseudomonas cepacia
Salmonella enteridis
Salmonella enteritidis
Salmonella choleraesuis
Salmonella paratyphi A
Salmonella typhimurium
Serratia marcescens (gram-negative aerobe)
Shigella dysenteriae
Shigella flexneri
Shigella sonnei
Staphylococcus aureus (gram-positive aerobe, responsible for "Golden Staph")**
Streptococcus faecalis (now classified as Enterococcus faecalis)
Streptococcus mutans (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
Streptococcus pneumoniae (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
Streptococcus pyogenes (beta-hemolytic Streptococcus), also known as Group B Streptococcus (GBS)
Streptococcus sanguis (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
Streptococcus viridans (alpha-hemolytic Streptococcus), also known as Group A Streptococcus (GAS)
Streptomyces species
Treponema pallidum
Ureaplasma urealyticum - a species of detrimental ureaplasma bacteria, a genus of bacteria belonging to the family Mycoplasmataceae. Mycoplasma, also known as Asterococcus, is a genus of aerobic to facultatively anaerobic, gram-negative detrimental bacteria. Several species are pathogenic in humans, including Mycoplasma fermentans, Mycoplasma genitalum and Mycoplasma pneumoniae. U. urealyticum - the phylogenetic cluster of M. pneumoniae, is part of the normal genital flora of both men and women. It is found in about 70 percent of sexually active humans. It is believed to be sexually transmitted and transmitted from mother to infant.
Ureaplasma urealyticum infection may cause urinary tract infections (UTIs), urinary tract/kidney stones (struvite stones), non-specific urethritis (NSU), nongonorrheal urethritis and prostatitis in men. It has also been noted as one of the infectious causes of sterile pyuria (pus in urine).
Penicillins are ineffective as U. urealyticum does not have a cell wall, which is the drug's main target.
Vancomycin-Resistant Enterococcus (VRE)
* PLEASE NOTE: Pseudomonas aeruginosa is a common bacterium found in soil, water, skin flora and most man-made environments. An opportunistic pathogen of immunocompromised individuals vulnerable to infections, it typically infects the pulmonary tract, urinary tract, burns, wounds, and also causes other blood infections.
P. aeruginosa is the third leading cause of hospital-acquired urinary tract infections, accounting for approximately 12 percent of all infections of this type. They are usually related to urinary tract catheterization, instrumentation or surgery.
It is a common cause of post-operative infection in radial keratotomy (RK) eye surgery patients and of "hot-tub rash" (dermatitis), caused by lack of proper periodic attention to water quality.
P. aeruginosa appears to be among the most adherent of common urinary pathogens to the bladder uroepithelium. An infection can occur via an ascending or descending route.
P. aeruginosa can also invade the bloodstream from the urinary tract. This route is the source of approximately 40 percent of P. aeruginosa infections.
P. aeruginosa can cause chronic opportunistic infections. These kinds of infections are a serious problem for medical care. Many patients, immunocompromised and the elderly in particular, often cannot be treated effectively with traditional antibiotic therapy.
As a highly relevant opportunistic pathogen, P. aeruginosa has low antibiotic susceptibility. It is naturally resistant to a large range of antibiotics and may demonstrate additional resistance after unsuccessful treatment.
Therefore, choosing an antibiotic should be guided according to laboratory sensitivities, rather than empirically. However, if antibiotics are started empirically - with some exceptions, given by injection only - then cultures should be obtained and, after having the culture results available, the choice of an antibiotic used should be carefully reviewed.
April 17, 2009:
Thanks, Andrew, for your advice and support with my Pseudomonas [aeruginosa] bladder infection with your amazing product Uribiotic which stopped the infection and kept it away.
I've suffered from UTIs for 18 years since my spinal cord injury and now I'm infection free.
JASON C.
Great Britain
** PLEASE NOTE: In case of Staphylococcus aureus infections, Uribiotic Formula can be a part of a combined antibiotic therapy as it may enhance the effectiveness of pharmaceutical antibiotics for the UTI treatment.
Uribiotic Formula: An Immune Booster
An immune-boosting Uribiotic Formula helps to increase the natural safeguards - bodily defense systems that protect the urinary tract against pathogenic, infection-causing bacteria, such as:
the flow of urine which functions as an antiseptic, helping to wash potentially harmful bacteria out of the body during normal urination. (Urine is normally sterile, that is, free of bacteria, viruses, and fungi!)
the ureters (muscular ducts that propel urine from the kidneys to the urinary bladder) and the bladder
the immune defenses and antibacterial substances in the mucous lining of the bladder
the bladder lining cells that, literally, sacrifice themselves and self-destruct to fight off detrimental bacteria (a process called apoptosis). In so doing, they fall away from the lining, carrying the bacteria with them. This process, suggested by some interesting research, eliminates about 90% of the E. coli
the vagina which is colonized - in normal fertile women - by lactobacilli, beneficial micro-organisms that maintain a highly acidic environment (low pH). Lactobacilli also produce hydrogen peroxide, which helps eliminate bacteria and reduces the ability of E. coli to adhere to vaginal cells
the so-called human beta-defensin-1 (HBD-1) which fights E. coli within the female urinary and reproductive tracts -.a possible natural antibiotic identified by some researchers
the antibacterial actions of some secretions of the prostate gland probably for why men are less likely than women to develop urinary tract infection.
Uribiotic Formula: Health Benefits Summary
It is so embarrassing having consult your doctor for the same reason (another infection!) and need to take another round of antibiotics.
The truth is, however, that urinatry tract infections CAN be successully remedied and prevented without multiple rounds of prescription medications (antibiotics).
Health benefits of our proprietary Uribiotic Formula - a synergistic blend of 59 nutrients, phytonutrients (plant nutrients) and herbs thoroughly researched and put to the test - include:
anti-inflammatory,
antibacterial,
antifungal,
antiviral,
antiparasitic,
antioxidant,
diuretic,
anti-edematous (decreasing edema and swelling), and
antitumor.
Thousands of people around the world have proven the efficacy of this approach. And what is most important, there has not been a single reported harm done by taking the Uribiotic Formula.
Uribiotic® The Genuine Mierzejewski Formula™
Advanced Urinary Tract Support *
63 Vegetarian Capsules
59 Phytonutrients and NutrientsSUPPLEMENT FACTS:
Amount Per Serving (3 Capsules)
Other ingredients: Hydroxypropylmethylcellulose (vegetable capsule), microcrystalline cellulose, vegetable stearate and silica.
This product is manufactured in a NSF GMP registered facility in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.
QUALITY & SAFETY ASSURANCE
Take 3 capsules 3 times daily in between meals (beginning after breakfast), each time with 4 ounces (˝ cup) of purified lukewarm water, or as recommended by a qualified healthcare professional.
DIRECTIONS
If you are under a physician’s care or taking medication, or if you are pregnant or nursing, consult your healthcare practitioner before using this product.
CAUTION
Quality and purity guaranteed. This product does not contain MSG, wheat, gluten, soy protein, fish, shellfish, milk/dairy, corn, egg, nuts, sugar, salt, starch, artificial coloring, preservatives, or flavoring.
PREMIUM PURITY
FULL OF HEALTH, INC. Since 1996 Uribiotic® Formula: Advanced Urinary Tract Support *
* This statement has not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.
Full of Health and Uribiotic are registered trademarks of Full of Health, Inc. BioPerine® is a registered trademark of Sabinsa Corporation.
Healing Properties
Uribiotic Formula can cause the almost instant disappearance of
the painful burning sensation when urinating,
the need for frequent urination,
the inability to empty the bladder completely even though you have the urge.
Uribiotic Formula can help you eliminate:
the harmful bacteria from the inside of the urinary tract and without disrupting the normal body functions.
Uribiotic Formula can help you prevent and remedy:
both acute and repeated (chronic) urinary tract infections, and
the need and dependence on antibiotics.
Recommended Intake
Upon the first signs of urinary tract infection, begin taking 3 capsules of the Uribiotic Formula3 times daily (morning - beginning after breakfast, noon, afternoon) 20 minutes apart from having food, each time with ˝ glass of purified lukewarm water.
Also do your best and try to sip lots of water throughout the day.
PLEASE NOTE: If necessary, Uribiotic Formula can be a part of a combined antibiotic therapy as it may enhance the effectiveness of pharmaceutical antibiotics for the treatment of urinary tract infections (UTIs), especially in case of Staphylococcus aureus infections.
First Signs of Relief Within 24-48 Hours
You should experience the first signs of relief within 24-48 hours after you begin taking the Uribiotic Formula. The symptoms should be cleared within 7 days, provided you will keep taking the Uribiotic Formula consistently without skipping doses.
However, the results may vary from person to person depending on the diagnosis, degree of UTI, age, sex and other existing health conditions.
Our Clients Write to Us:
April 29, 2011
Hello, again, Full of Health Team!
I just got on to your website to order more URIBIOTIC... I am the "Katie B." from Denver, Colorado! My testimonial has been on your home page for over 2 years now.
I have been living in China for the past year and I just recently got a bladder infection for the first time in over 2 years!
You have no idea how comforting it has been to have the assurance of having your product in my medicine cabinet while living in such a foreign land with foreign doctors and hospitals.
I was quite scared when I got the bladder infection a couple of days ago, because I thought, "what if it just doesn't work this time and I have to go to a hospital in China?!"
But, have no fear… URIBIOTIC worked for me AGAIN!
THANK YOU FOR YOUR AMAZING PRODUCT!!!! I sing your praises every time I have sex -:)
Thank you and have a great weekend!
Katie
June 19, 2009
Thanks, Andrew!
I got a severe bladder infection and also discovered I had an enlarged prostate. I was in bad pain when I often had to go to restroom. One night I was going every 30 minutes.
They put me on sulfa antibiotics and also wanted me to take Flowmax which I told them I would not take. I don't like taking antibiotics if I can help it.
They also did a CAT scan. I took the antibiotics for a few days but they did not help that much.
Until I got my I order of Uribiotic in. I started taking it and, after a few days, noticed feeling a little better each day.
I started going to the bathroom about twice a night. Then just once a night and now I never wake to go to the bathroom. My measured urine outflow in the morning became normal and with no pain.
I was also taking DP Extract for my enlarged prostate for about six weeks. Then I went to a specialist and he checked me and said that my prostate was normal. He said I don't need to come back.
Now everything is back to normal. I still take both Uribiotic and DP Extract.
I am very thankful for your help and advice, Andrew.
Aaron Hiller
Texas
July 14, 2007
Problem solved! The infection is GONE! I just thought you might want to know this in case you get any customers notifying you that URIBIOTIC doesn't seem to be working.
I love your product and continue to rave and refer anyone I talk to about UTIs to your
website.
THANK YOU FOR CREATING THIS PRODUCT!!!
Katie B.
Denver, Colorado
No Side Effects
Formulated with care by a master formulator and manufactured according to the highest standards *, this unique synergistic combination can help you deal with your bladder and/or even kidney infection:
safely,
effectively, and
with no side effects.
* QUALITY & SAFETY ASSURANCE: Uribiotic Formula is manufactured in accordance with cGMPs for Nutritional Supplements in accordance with USP 31. The laboratories are ISO 9001:1994 certified and ISO 17025:2005 accredited. Raw materials used in the manufacturing of this product are in full compliance with the Bioterrorism Preparedness and Response Act of 2002. Raw material safety and quality is ensured by the manufacturer's Supplier Qualification Program.
Cautions and Contraindications
Sexual System: Uribiotic Formula is not recommended to be taken during pregnancy as it can cause contractions of the uterus due to presence of Goldenseal, Vinpocetine and hydroquinone (via arbutin present in Uva Ursi/Bearberry).
Cardiovascular System: Uribiotic Formula should be consumed with caution by patients with severe hypertension (high blood pressure) due to the presence of Nettle root as it may further raise blood pressure in some people. However, Olive Leaf Extract, Rutin and Siberian Ginseng (Eleutherococcus senticosus) present in the Uribiotic Formula may actually help lower blood pressure in hypertension patients.
Pharmaceutical Drugs: Uribiotic Formula should be consumed with caution by patients on a high dose of warfarin (blood thinner) due to the presence of garlic which may potentiate the anticoagulant effects of warfarin. (Reference: Fugh-Berman, A. Herb-drug interactions. Lancet. 355(9198):134-138, 2000).
PLEASE NOTE: When acute nephritis (kidney infection) is present - accompanied by high fever along with sudden retention of urine (a painful urge to pass urine but the inability to do so) - have your condition assessed immediately by your physician.
Simple and Astonishingly Effective
Our proprietary Uribiotic Formula is so simple and astonishingly effective that it continues to amaze even the most skeptical people.
For this reason, we have decided to go worldwide and share our experience with the public on the Internet to help people around the world to remedy bladder and/or even kidney infection.
So far, we have introduced our proprietary Uribiotic Formula to our clients and customers in 32 countries: the United States, Australia, the United Kingdom, South Africa, New Zealand, Germany, Belgium, Mexico, Italy, Singapore, France, Russia, Croatia, Poland, Portugal, Denmark, United Arab Emirates, Hong Kong, St. Lucia (West Indies), Norway, Saudi Arabia, Turkey, Slovenia, Greece, Qatar, Jordan, Israel, the Netherlands, Luxembourg, Sri Lanka, India, and Spain.
With no doubt this superb supplement can be of great benefit to you. You have nothing to lose - and lots to gain. And if necessary, it can be a part of a combined antibiotic therapy as Uribiotic Formula may even enhance the effectiveness of standard pharmaceutical antibiotics for the treatment of urinary tract infections (UTIs), especially in case of Staphylococcus aureus infections.
Therapeutic and Preventive Intake: Directions
With possible variations from person to person, the suggested intake of the Uribiotic Formula - depending on the diagnosis, degree of UTI, sex, age and other existing health conditions - can be described as follows:
I. Acute UTI:
In case of first signs of discomfort (slight burning sensation when urinating, frequent urination and/or inability to empty bladder completely) you need to take:
3 capsules 3 times daily; therefore, for full benefits, at least 1 bottle of the Uribiotic Formula is needed (an initial 7-day therapeutic intake).
In case persistent signs of UTI (painful burning sensation when urinating, frequent urination at night and/or inability to empty bladder completely) you need to take:
3 capsules 3 times daily; therefore, for full benefits, 2 bottles of the Uribiotic Formula are needed (an extended 14-day therapeutic and prophylactic intake).
II. Chronic/Repeated UTI:
In case of recurrent, repeated UTIs (all the above symptoms along with the need and dependence on antibiotics) it is necessary to take:
3 capsules 3 times daily; therefore, for full benefits, 3 bottles of the Uribiotic Formula are needed (an intensive 21-day therapeutic and prophylactic intake)
DIRECTIONS: Take the capsules throughout the day in between meals (on an empty stomach), preferably before 6 pm, each time with ˝ glass of purified lukewarm water.
PLEASE NOTE: After all symptoms have disappeared, in order to restore the urinary tract’s normal pH and, thus, prevent recurring UTIs, taking 1 capsule of the Uribiotic Formula 3 times daily for at least 7 consecutive days is highly recommended.
ADDITIONAL RECOMMENDATION: In order to fully exert the therapeutic, protective and preventive (prophylactic) effects of the Uribiotic Formula, it might be taken along with probiotics in order to suport friendly urogenital flora, such as Probiotic LGG Plus: Friendly Urogenital Flora Support.
CAUTIONS:Uribiotic Formula is not recommended for pregnant women. Also patients with severehypertension (high blood pressure) should take it with caution. However, Olive Leaf Extract, Rutin and Siberian Ginseng (Eleutherococcus senticosus) present in the Uribiotic Formula may actually help lower blood pressure in hypertension patients). It should also be taken with caution by patients on aaa high dose of warfarin (blood thinner) due to the presence of garlic which may potentiate the anticoagulant effects of warfarin. (Reference: Fugh-Berman, A. Herb-drug interactions. Lancet. 355(9198):134-138, 2000).
PLEASE NOTE: When acute nephritis (kidney infection) is present - accompanied by high fever along with sudden retention of urine (a painful urge to pass urine but the inability to do so) - have your condition assessed immediately by your physician.
Do Not Stop!
Although symptoms-free, please DO NOT stop taking the Uribiotic Formula and continue to use it until the bottle is empty (up to 7 days).
If you are prone to repeated/chronic urinary tract infections keep an extra bottle of the Uribiotic Formula on hand and use it immediately at the first signs of infection for the minimum of 3 consecutive days.
In time, you will notice that the frequency of your urinary tract infections begins to seize, making the further use of the Uribiotic Formula - with some possible exceptions - unnecessary and/or occasional only.
Male Adults with BPH: Although we have found the Uribiotic Formula effective in both women and men, the latter - besides bladder infections - quite offten suffer from undiagnosed prostate infection (prostatitis) and/or benign prostatic hyperplasia (BPH), a non-cancerous swelling of the prostate gland.
Uribiotic Orders: United States and Worldwide (Except in Canada)
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Bladder Infections in Paraplegia (SCI)
Neurological conditions like paraplegia, a spinal cord injury, also called spinal
cord impairment (SCI), usually result in a neurogenic bladder - an unstable or
atonic bladder (with no muscle tone).
People with spinal cord injuries have lost, partial or complete, control over their bladder and sphincter due to the compromised nerve receptors that are responsible
for:
contracting and relaxing the muscles of the bladder and the sphincter, and
registering feelings of pressure or release.
Due to this condition, most paraplegics are exposed to the regular use of catheters and drugs. (The more traditional cap and bag, with continual drainage, is falling from favor even though it is a safer system).
However, catheters often increase the risk of the urinary tract injuries and repeated
bladder infections - a common problem in people with spinal cord impairment.
Exposed to repeated or long-term courses of antibiotics, in time, they also develop resistance to drugs what makes maintaining healthy urinary tract for them even more difficult.
Contrary to a popular belief and common medical practice, people with spinal cord injuries or spinal cord impairment do NOT have to:
suffer from chronic bladder-kidney infections and
be exposed to vicious antibiotics.
It is our clinical experience that paraplegics, expecially those who use catheters, can successfully remedy, and most importantly, prevent bladder infections with the help of our proprietary UTI Uribiotic Formula.
Therefore, you, or someone you know or hold dear, who suffers from spinal cord injury, should give this superb herbal blend serious consideration.
Our Clients with SCI Write to Us: Testimonials
June 29, 2011:
I have been quadriplegic for 15 years. About seven years ago, I started to suffer recurrent urinary tract infections to the point where most of the bacteria had become multiresistant.
My urologist pointed out to me that kidney failure is the biggest killer of people with spinal cord injuries as a result of repeated urinary tract infections which became untreatable as a result of repetitive use of antibiotics.
About two years ago I developed an infection, the bacteria being pseudomonas. Antibiotics did not work and the decision was made to not use any more, live with it and hope it didn't get into my bloodstream.
I couldn't accept this, so I researched the Internet once again until I finally found out about oil of oregano and Uribiotic. I ordered some, showed my GP who confirmed that there was nothing in it that could possibly cause any harm and to give it a go, which I did.
Within a few weeks the urinary tract infection cleared up.
I have barely had any symptoms since, and when I do I just use the Uribiotic for a couple of days and symptoms clear up. No side effects and no worries about the tablets not working.
I am a skeptic and honestly didn't think this would work when I tried it, but it does. If I didn't find out about it, I hate to think where I would be now.
I just wish I knew about it sooner.
Janine N.
Perth, Western Australia
April 17, 2009:
Thanks, Andrew, for your advice and support with my Pseudomonas [aeruginosa] bladder infection with your amazing product Uribiotic which stopped the infection and kept it away.
I've suffered from UTIs for 18 years since my spinal cord injury and now I'm infection free.
JASON C.
Great Britain
December 14, 2007:
As a paraplegic for almost 14 years, I was almost constantly on antibiotics due to
chronic bladder infection. However, being afraid of possible side effects, for many
years I was reluctant to consider any natural alternatives.
I was afraid of getting diarrhea or constipation. These are the worst - a real disaster!
But after successful experience with D-Mannose, I started looking for other
natural means to solve my problem.
And I was pleasantly surprised by lack of any adverse reactions to URIBIOTIC,
which I introduced to my system very cautiously.
Two weeks later, my urine culture showed NO E. coli. Burning went away in a
few days. I'm pleased to report such great results.
Barret D.
Minnesota
If Your Infection Persists
On rare occasions the Uribiotic Formula alone does not seem to be enough, especially
when the infection has already spread into the entire urinary tract, the following remedies should
be given serious consideration:
Although we have found the Uribiotic Formula effective in both women and men, the latter - besides bladder infections - quite offten suffer from undiagnosed prostate infection (prostatitis) and/or benign prostatic hyperplasia (BPH), a non-cancerous swelling of the prostate gland.